Exploring the Chemical Properties and Synthesis of 4-(Trifluoromethoxy)benzonitrile
Understanding the fundamental chemical and physical properties of a compound is crucial for its effective utilization in various scientific and industrial applications. 4-(Trifluoromethoxy)benzonitrile (CAS 332-25-2) is a compound that has garnered significant interest due to its distinctive trifluoromethoxy group and its broad applicability, particularly as a versatile building block in organic synthesis. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing comprehensive information on such key intermediates.
Physically, 4-(Trifluoromethoxy)benzonitrile typically presents as a colorless to almost colorless clear liquid. Its boiling point is around 192-193 °C, with a density of approximately 1.285 g/mL at 25 °C. The refractive index is noted as n20/D 1.452. These properties make it suitable for various reaction conditions commonly employed in fine chemical synthesis. The molecular formula C8H4F3NO and a molecular weight of 187.12 further define its composition and reactivity.
The synthesis of 4-(Trifluoromethoxy)benzonitrile often involves multi-step processes starting from readily available precursors. For example, synthetic routes may involve the cyanation of corresponding aryl halides or the functionalization of substituted benzene rings. The presence of the trifluoromethoxy group poses unique challenges and opportunities in synthesis, often requiring specialized reagents and carefully controlled reaction conditions to maintain its integrity and reactivity. Researchers looking to buy 4-Trifluoromethoxybenzonitrile for their synthesis projects rely on suppliers who can guarantee high purity and consistent quality, such as NINGBO INNO PHARMCHEM CO.,LTD.
The CAS 332-25-2 chemical properties are key to its broad utility. The nitrile group is a highly reactive functional group that can undergo a wide array of transformations, including hydrolysis to carboxylic acids, reduction to amines, and nucleophilic additions. The trifluoromethoxy group, being strongly electron-withdrawing and lipophilic, can influence the electronic distribution within the molecule and modify its physical and biological properties. This makes 4-(Trifluoromethoxy)benzonitrile an excellent starting point for the synthesis of pharmaceuticals, agrochemicals, and advanced materials. Many scientific publications detail the use of this compound in complex organic synthesis, highlighting its role as a valuable building block.
As a trusted 4-Trifluoromethoxybenzonitrile supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. ensures that the product delivered meets stringent purity standards required for demanding applications. Our expertise in chemical synthesis and quality control guarantees that researchers and manufacturers receive reliable intermediates for their projects. Whether for academic research or industrial production, understanding the properties and sourcing strategies for compounds like this is essential.
In conclusion, 4-(Trifluoromethoxy)benzonitrile is a compound of significant chemical interest due to its favorable physical properties and the versatile reactivity offered by its functional groups. Its importance as a building block in organic synthesis is undeniable, paving the way for innovations across multiple industries. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing access to high-quality intermediates like CAS 332-25-2 to support these advancements.
Perspectives & Insights
Data Seeker X
“As a trusted 4-Trifluoromethoxybenzonitrile supplier in China, NINGBO INNO PHARMCHEM CO.”
Chem Reader AI
“ensures that the product delivered meets stringent purity standards required for demanding applications.”
Agile Vision 2025
“Our expertise in chemical synthesis and quality control guarantees that researchers and manufacturers receive reliable intermediates for their projects.”