In the intricate landscape of chemical synthesis, certain molecules stand out for their versatility and critical role in creating advanced compounds. One such molecule is 4-Amino-3-iodobenzotrifluoride, identified by its CAS number 163444-17-5. This compound, a specialized aromatic amine, is a cornerstone for innovation across various industries, including pharmaceuticals, agrochemicals, and materials science. NINGBO INNO PHARMCHEM CO.,LTD. is a prominent supplier, ensuring high-quality access to this essential building block.

Chemical Identity and Key Properties

4-Amino-3-iodobenzotrifluoride, also known by its IUPAC name 2-Iodo-4-(trifluoromethyl)aniline, possesses a unique molecular structure characterized by a benzene ring substituted with an amino group, an iodine atom, and a trifluoromethyl group. Its molecular formula is C7H5F3IN, with a molecular weight of approximately 287.02 g/mol. Typically appearing as a white to off-white powder, it boasts a high purity assay, often exceeding 98.0%. This purity is paramount for its downstream applications, where precise reactions and minimal byproducts are essential.

The compound’s physical properties, such as a melting point around 50°C and specific density, contribute to its stability under controlled conditions. The trifluoromethyl (-CF3) group imparts electron-withdrawing capabilities and enhances lipophilicity, while the iodine atom provides a reactive site for various coupling reactions, such as Suzuki or Heck couplings. The amino group further contributes to its reactivity, enabling participation in a range of organic transformations.

Role in Organic Synthesis and Industrial Applications

The significance of 4-Amino-3-iodobenzotrifluoride in organic synthesis cannot be overstated. It serves as a crucial intermediate, allowing chemists to build complex molecular architectures. In the pharmaceutical industry, it acts as a vital building block for synthesizing active pharmaceutical ingredients (APIs). The incorporation of the trifluoromethyl group can improve drug properties like metabolic stability and bioavailability, making it invaluable in drug discovery and development. For instance, research into targeted cancer therapies often involves intermediates like this, where precise molecular modifications are key to efficacy.

Beyond pharmaceuticals, its applications extend to agrochemicals. It is instrumental in the development of next-generation pesticides and herbicides, where its unique chemical structure contributes to enhanced potency and selectivity. The demand for effective and environmentally conscious agrochemical solutions continues to drive the need for such specialized intermediates.

In materials science, 4-Amino-3-iodobenzotrifluoride is explored for its potential in creating advanced materials. Fluorinated compounds are known for their exceptional thermal stability, chemical resistance, and unique electronic properties, making them suitable for high-performance polymers, OLEDs, and other advanced applications.

Sourcing High-Quality Intermediates

For businesses requiring reliable access to 4-Amino-3-iodobenzotrifluoride, sourcing from reputable suppliers like NINGBO INNO PHARMCHEM CO.,LTD. is crucial. Their commitment to quality ensures that the product meets stringent industry standards, guaranteeing consistent performance in demanding synthetic processes. Companies can buy 4-Amino-3-iodobenzotrifluoride with confidence, knowing they are receiving a product that supports their research and production goals. Whether for laboratory-scale research or industrial production, the availability of this intermediate facilitates innovation and advancement in chemical manufacturing.

As industries continue to push the boundaries of chemical innovation, the demand for versatile and high-purity intermediates like 4-Amino-3-iodobenzotrifluoride will only grow. Its established utility and ongoing research into new applications solidify its position as an indispensable component in the modern chemical toolkit.