Ethyl cyclopropanecarboxylate (CAS 4606-07-9) is a fascinating organic compound that chemists leverage for its unique structural features and reactivity. Characterized as a colorless transparent liquid, this ester plays a crucial role as a synthetic intermediate, finding widespread use in both academic research and industrial manufacturing. Understanding its synthesis pathways and application spectrum is key for any professional in the field.

The synthesis of ethyl cyclopropanecarboxylate can be achieved through various methods. One notable approach involves the reaction of cyclopropanecarboxylic acid with ethanol, typically in the presence of an acid catalyst, forming the desired ester. Another efficient method, particularly for research purposes, involves the use of ethyl diazoacetate in conjunction with gold catalysts, which can convert ethylene into ethyl cyclopropanecarboxylate with moderate yields under mild conditions. These synthesis routes ensure its availability for a range of chemical needs.

The applications of ethyl cyclopropanecarboxylate are extensive. It serves as a valuable precursor for synthesizing a diverse array of cyclopropane derivatives, which are sought after in drug discovery and material science due to their unique steric and electronic properties. Furthermore, it acts as an annulation reagent in reactions like Friedel-Crafts acylation, enabling the creation of cyclic structures such as 2-methylindanones. This versatility makes it a compound of interest for chemists aiming to expand their synthetic toolbox.

For industries requiring a consistent and high-quality supply, purchasing ethyl cyclopropanecarboxylate from a reliable manufacturer is paramount. Key considerations include purity levels (often specified as ≥98.5%), physical properties like boiling point (130-135°C), and appropriate packaging (e.g., 200 kg drums). When searching for a supplier, particularly in China, focusing on those with established quality control processes and manufacturing capacity ensures that your procurement meets the rigorous demands of your applications, whether for laboratory research or large-scale production.

In conclusion, ethyl cyclopropanecarboxylate is a compound of significant value in organic chemistry. Its accessible synthesis and diverse applications as a building block and reaction reagent underscore its importance. As a premier manufacturer and supplier, we are dedicated to providing this essential chemical to support your innovative research and industrial production needs.