Exploring the Synthesis and Properties of 2,2-Difluoroethanol
2,2-Difluoroethanol (CAS: 359-13-7) is a compound of significant interest in the chemical industry, primarily due to its utility as a versatile organic synthesis building block. Its unique structure, featuring two fluorine atoms on the alpha-carbon of an ethanol backbone, imparts distinct chemical and physical properties that make it valuable across various sectors. NINGBO INNO PHARMCHEM CO.,LTD. offers high-quality 2,2-Difluoroethanol, understanding the intricacies of its synthesis and application.
The synthesis of 2,2-Difluoroethanol can be achieved through several established methods. Common routes include the reduction of difluoroacetic acid esters or related compounds using reducing agents like lithium aluminum hydride or catalytic hydrogenation. These methods require careful control of reaction conditions to ensure high yield and purity. For industrial-scale production, catalytic hydrogenation methods are often favored for their efficiency and scalability. Our commitment as a manufacturer in China means we employ optimized synthesis processes to deliver a product that meets stringent quality specifications.
Physically, 2,2-Difluoroethanol is a colorless, transparent liquid. Its key properties include a relatively low melting point of -28°C and a boiling point of approximately 95.5°C at standard atmospheric pressure. The compound is also noted for its flash point, indicating its flammable nature, which necessitates proper handling and storage in cool, well-ventilated areas. The assay is typically ≥98.0%, underscoring its suitability for demanding chemical synthesis applications.
The chemical reactivity of 2,2-Difluoroethanol is significantly influenced by the electron-withdrawing effect of the fluorine atoms. This makes the hydroxyl hydrogen more acidic compared to ordinary ethanol, and it participates readily in reactions such as esterification and etherification. Its role as a fluorinated building block is crucial; it allows chemists to introduce the difluoroethyl moiety into larger molecules, thereby modifying their lipophilicity, metabolic stability, and binding characteristics. This is particularly beneficial when looking to buy 2,2-Difluoroethanol for use in the pharmaceutical and agrochemical industries.
NINGBO INNO PHARMCHEM CO.,LTD. prides itself on being a reliable source for 2,2-Difluoroethanol. Our understanding of its synthesis and properties allows us to provide a product that consistently meets the high standards required for advanced chemical manufacturing. Whether you require this compound for organic synthesis, pharmaceutical research, or material science applications, our expertly manufactured 2,2-Difluoroethanol is designed to meet your needs.
The synthesis of 2,2-Difluoroethanol can be achieved through several established methods. Common routes include the reduction of difluoroacetic acid esters or related compounds using reducing agents like lithium aluminum hydride or catalytic hydrogenation. These methods require careful control of reaction conditions to ensure high yield and purity. For industrial-scale production, catalytic hydrogenation methods are often favored for their efficiency and scalability. Our commitment as a manufacturer in China means we employ optimized synthesis processes to deliver a product that meets stringent quality specifications.
Physically, 2,2-Difluoroethanol is a colorless, transparent liquid. Its key properties include a relatively low melting point of -28°C and a boiling point of approximately 95.5°C at standard atmospheric pressure. The compound is also noted for its flash point, indicating its flammable nature, which necessitates proper handling and storage in cool, well-ventilated areas. The assay is typically ≥98.0%, underscoring its suitability for demanding chemical synthesis applications.
The chemical reactivity of 2,2-Difluoroethanol is significantly influenced by the electron-withdrawing effect of the fluorine atoms. This makes the hydroxyl hydrogen more acidic compared to ordinary ethanol, and it participates readily in reactions such as esterification and etherification. Its role as a fluorinated building block is crucial; it allows chemists to introduce the difluoroethyl moiety into larger molecules, thereby modifying their lipophilicity, metabolic stability, and binding characteristics. This is particularly beneficial when looking to buy 2,2-Difluoroethanol for use in the pharmaceutical and agrochemical industries.
NINGBO INNO PHARMCHEM CO.,LTD. prides itself on being a reliable source for 2,2-Difluoroethanol. Our understanding of its synthesis and properties allows us to provide a product that consistently meets the high standards required for advanced chemical manufacturing. Whether you require this compound for organic synthesis, pharmaceutical research, or material science applications, our expertly manufactured 2,2-Difluoroethanol is designed to meet your needs.
Perspectives & Insights
Core Pioneer 24
“offers high-quality 2,2-Difluoroethanol, understanding the intricacies of its synthesis and application.”
Silicon Explorer X
“The synthesis of 2,2-Difluoroethanol can be achieved through several established methods.”
Quantum Catalyst AI
“Common routes include the reduction of difluoroacetic acid esters or related compounds using reducing agents like lithium aluminum hydride or catalytic hydrogenation.”