NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing comprehensive information about the chemical intermediates we supply, empowering our clients with the knowledge needed for effective utilization. Today, we delve into the synthesis and properties of 4-Chloro-2-methylpyridine (CAS 3678-63-5), a compound of significant importance in various industrial applications, from pharmaceuticals to agrochemicals.

Understanding the chemical properties of 4-Chloro-2-methylpyridine is crucial for its successful application. Typically appearing as a colorless to light yellow liquid, it possesses a pungent odor. Its boiling point is approximately 170-172°C, with a density around 1.156 g/cm³ at 20°C. While slightly soluble in water, it exhibits good solubility in common organic solvents like ethanol and ether. These physical characteristics influence its handling, storage, and its behavior in various reaction systems. The chemical stability of 4-Chloro-2-methylpyridine is generally good due to its aromatic pyridine ring, but it can participate in reactions like nucleophilic substitution, particularly at the chlorine atom, making it a valuable reactive intermediate.

The synthesis of 4-Chloro-2-methylpyridine can be achieved through several routes. Common methods involve the chlorination of 2-methylpyridine or the functional group transformation of other pyridine derivatives. Transition metal-catalyzed coupling reactions are also employed. Each method requires careful control of reaction conditions, temperature, pressure, and catalysts to achieve high purity and yield. NINGBO INNO PHARMCHEM CO.,LTD. focuses on optimized manufacturing processes to ensure the consistent quality and high assay (≥99.0%) that our clients expect, making us a reliable supplier for your 4-Chloro-2-methylpyridine needs.

Proper storage and transportation of 4-Chloro-2-methylpyridine are essential for maintaining its integrity and ensuring safety. It should be stored in a cool, dry, and well-ventilated place, away from heat sources and incompatible materials such as strong oxidizers, acids, and bases. During transportation, it is vital to adhere to relevant regulations, ensuring containers are properly sealed and secured to prevent leakage. Emergency preparedness, including appropriate fire-fighting and spill containment equipment, is also a critical aspect of handling this chemical.

As a leading supplier, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-quality 4-Chloro-2-methylpyridine at competitive prices. We offer flexible packaging and customized solutions to meet diverse project requirements. Whether you are looking to purchase 4-Chloro-2-methylpyridine for pharmaceutical research, agrochemical development, or other fine chemical applications, we are your trusted partner. Contact us today to learn more about the technical specifications, availability, and to get a quote for 4-Chloro-2-methylpyridine.