Periodic Acid, identified by its CAS number 10450-60-9, is a powerful oxidizing agent with significant industrial relevance. Understanding its synthesis is key to appreciating its availability and application across various sectors, from organic chemistry to life sciences.

The production of Periodic Acid typically involves the oxidation of iodate salts. A common industrial method entails the electrochemical oxidation of sodium iodate in an alkaline solution using a lead dioxide anode. Alternatively, chemical oxidation using chlorine can also achieve the desired transformation. These methods ensure a steady supply of Periodic Acid for various applications. The efficiency and purity achieved through these periodic acid synthesis methods are critical for its industrial use.

In laboratory settings, a classic preparation method involves treating tribarium dihydrogen orthoperiodate with nitric acid. The resulting barium nitrate, being less soluble, precipitates out, allowing for the isolation of periodic acid. This process, while effective for smaller scales, highlights the chemical principles behind its formation. Exploring how periodic acid is made provides insight into its handling and properties.

The industrial demand for Periodic Acid stems from its versatile applications. As a potent oxidizing agent, it plays a crucial role in organic synthesis, notably in the Malaprade reaction for cleaving vicinal diols. Its application in the Periodic Acid-Schiff (PAS) staining technique is fundamental in histology for identifying carbohydrates. Furthermore, it serves as a valuable pharmaceutical intermediate and is used in industrial processes like silk screen reclamation. The reliability of its supply chain, supported by manufacturers like NINGBO INNO PHARMCHEM CO.,LTD., ensures that industries can consistently access this important chemical.

The properties of Periodic Acid, such as its crystalline form and solubility, contribute to its ease of use in various applications. However, its strong oxidizing nature necessitates careful handling and storage, adhering to safety guidelines. The ongoing research into its applications further cements its position as a key chemical in numerous scientific and industrial endeavors.

In summary, the synthesis of Periodic Acid is well-established, ensuring its availability for critical applications. Its multifaceted roles underscore its importance as an industrial chemical, driven by its powerful oxidizing properties and specific reactivity patterns.