In the realm of specialized chemical synthesis, understanding the properties and applications of key intermediates is fundamental. Heptamethyldisilazane, commonly known as HPMDS and identified by CAS number 920-68-3, is one such compound that plays a significant role, particularly in the pharmaceutical and agrochemical sectors. This article aims to provide a comprehensive overview of HPMDS, from its basic characteristics to its critical applications, and guide potential buyers on where to find reliable sources. As a leading fine chemical manufacturer and supplier based in China, we offer insights into this valuable chemical.

What is Heptamethyldisilazane (HPMDS)?

Heptamethyldisilazane is an organosilicon compound that presents as a colorless, transparent liquid. Its molecular formula is (CH3)3SiN(CH3)Si(CH3)3. Key physical and chemical properties include:

  • Appearance: Colorless transparent liquid.
  • Purity: Typically offered at a high purity of 99% or more (e.g., ≥ 99%).
  • Solubility: Insoluble in water but readily soluble in most organic solvents, facilitating its use in various reaction media.
  • Reactivity: It reacts with acids to form salt compounds.
  • Boiling Point: Approximately 147-150 °C.
  • Density: Around 0.739 g/cm³ at 25 °C.

These properties make it a stable and versatile reagent for specific chemical transformations.

Primary Applications of HPMDS

The predominant application of Heptamethyldisilazane is as a group protective agent. This function is invaluable in complex organic synthesis, where specific reactive sites on a molecule need to be temporarily deactivated to allow reactions to occur elsewhere in the molecule without interference. Its use is particularly prevalent in:

  • Pharmaceutical Production: HPMDS is a critical intermediate in the synthesis of various active pharmaceutical ingredients (APIs) and drug intermediates. It helps protect sensitive functional groups like hydroxyl (-OH) or amino (-NH2) groups during multi-step reaction sequences, ensuring higher yields and purity of the target drug molecule.
  • Agrochemical Synthesis: In the development and manufacturing of pesticides, herbicides, and other crop protection chemicals, HPMDS serves a similar protective role. It aids in the precise construction of complex agrochemical molecules, contributing to their efficacy and specificity.
  • Veterinary Drug Manufacturing: Similar to human pharmaceuticals, HPMDS is employed in the synthesis of veterinary APIs, ensuring the efficient production of animal health products.

Where to Buy Heptamethyldisilazane (HPMDS)

For R&D scientists, formulation chemists, and procurement managers seeking to buy HPMDS, identifying a reliable supplier is key. China is a significant global hub for the manufacturing of such fine chemical intermediates. When looking for a manufacturer or supplier of HPMDS CAS 920-68-3, consider the following:

  • Supplier Reputation: Look for established companies with a strong track record in the chemical industry.
  • Quality Assurance: Verify that the supplier adheres to strict quality control standards and can provide essential documentation like TDS and COA.
  • Production Capacity: Ensure the supplier can meet your volume requirements, whether for laboratory research or large-scale manufacturing.
  • Competitive Pricing: Obtain quotes from multiple suppliers to ensure you are getting a fair market price for your purchase.

Why Choose Us as Your HPMDS Supplier?

As a leading chemical manufacturer and supplier in China, we specialize in providing high-quality Heptamethyldisilazane. Our commitment to excellence ensures that our products meet the stringent demands of the pharmaceutical and agrochemical industries. We offer competitive pricing for HPMDS, available in standard 160kg iron drums, and our efficient logistics ensure timely delivery. We invite you to contact us to request a quote, inquire about pricing, or discuss your specific needs for HPMDS. We are dedicated to supporting your chemical synthesis endeavors with reliable products and exceptional service.

In conclusion, Heptamethyldisilazane (HPMDS) CAS 920-68-3 is a vital organosilicon intermediate that empowers precise chemical synthesis. Its application as a protective agent makes it indispensable in the creation of advanced pharmaceuticals and agrochemicals. By partnering with a trusted China manufacturer and supplier, you can ensure access to this critical compound for your research and production needs.