The intricate landscape of cancer research demands precise tools for understanding cellular behavior and identifying therapeutic targets. IR-780 Iodide (CAS: 207399-07-3) has emerged as a critical near-infrared (NIR) fluorescent dye, specifically enabling the detailed characterization of human Cancer Stem Cells (CSCs). Its unique optical properties and biological interactions make it indispensable for researchers seeking to unravel CSC mechanisms and develop more effective treatments.

At its core, IR-780 Iodide functions by facilitating the analysis of the HIF-1α/glycolysis dependent mitochondrial transporter ABCB10's activity. This allows researchers to precisely identify and study CSCs, which are often implicated in tumor initiation, metastasis, and therapeutic resistance. The dye's ability to emit light in the near-infrared spectrum is particularly advantageous for deep-tissue imaging and for minimizing interference from cellular autofluorescence, providing clearer signals for analysis. If you're looking to buy IR-780 Iodide, its specificity in this research area is a key benefit.

The dye typically presents as a gold green liquid with a high purity, often exceeding 98%, ensuring the accuracy and reproducibility of experimental results. For research institutions and pharmaceutical companies, sourcing high-quality IR-780 Iodide from reliable suppliers is crucial. Manufacturers and distributors, particularly those based in China, are prominent sources for this specialized chemical, offering competitive pricing and a stable supply chain.

Beyond CSC characterization, the advanced imaging capabilities of IR-780 Iodide are also being explored in other cancer research contexts, including photothermal therapy (PTT) and photodynamic therapy (PDT). Its strong absorption in the NIR region allows for efficient energy conversion when exposed to specific laser wavelengths, offering potential for targeted cancer cell destruction.

For procurement professionals and principal investigators, understanding the technical specifications and sourcing options for IR-780 Iodide is a strategic priority. When you inquire about purchasing this dye, it's beneficial to look for suppliers that provide comprehensive data, including its molecular formula (C36H44ClIN2) and information on its solubility and stability. This ensures that the purchased reagent will perform optimally within your experimental setup.

In conclusion, IR-780 Iodide is a powerful chemical tool that significantly advances our ability to study and target cancer stem cells. Its role in precise cellular characterization and its potential in therapeutic applications highlight its importance. By securing high-purity IR-780 Iodide from trusted manufacturers, researchers can enhance their imaging capabilities and make significant strides in cancer research and treatment development.