1-Bromo-4,5-difluoro-2-nitrobenzene, identified by CAS number 321-17-5, is a powerful and versatile intermediate in the realm of chemical synthesis. Its unique molecular structure, featuring a benzene ring substituted with bromine, two fluorine atoms, and a nitro group, equips it with distinct reactivity profiles. This makes it an indispensable compound for chemists engaged in the development of advanced materials, pharmaceuticals, and agrochemicals. Understanding its applications is key for researchers and manufacturers looking to leverage its potential.

Versatile Building Block in Organic Synthesis

As a brominated and fluorinated nitrobenzene derivative, 1-Bromo-4,5-difluoro-2-nitrobenzene is a prime candidate for a multitude of cross-coupling reactions, such as Suzuki, Sonogashira, and Buchwald-Hartwig couplings. These reactions allow for the facile introduction of various functional groups and carbon skeletons, facilitating the construction of complex molecular architectures. For instance, the bromine atom can be readily substituted or coupled, while the fluorine atoms influence electron density and metabolic stability in downstream products. Researchers often seek to purchase this compound to explore novel synthetic pathways.

Significance in Pharmaceutical Development

The pharmaceutical industry extensively utilizes fluorinated aromatic compounds due to their ability to enhance drug efficacy, improve pharmacokinetic properties, and increase metabolic stability. 1-Bromo-4,5-difluoro-2-nitrobenzene serves as a critical intermediate in the synthesis of numerous API candidates. Its strategic incorporation into drug molecules can lead to enhanced binding affinity to target proteins and improved oral bioavailability. Pharmaceutical companies often rely on dependable manufacturers to buy this chemical for their drug discovery pipelines.

Role in Agrochemical Innovation

Similarly, in the agrochemical sector, fluorinated compounds play a vital role in creating potent and selective pesticides, herbicides, and fungicides. The introduction of fluorine atoms can modify the biological activity and environmental persistence of agricultural chemicals. 1-Bromo-4,5-difluoro-2-nitrobenzene can be a key precursor in synthesizing new crop protection agents, contributing to more efficient and sustainable agriculture. Agricultural research institutions and manufacturers frequently look for suppliers offering this intermediate.

Sourcing and Availability

For those looking to procure 1-Bromo-4,5-difluoro-2-nitrobenzene, identifying a reliable manufacturer and supplier is essential. A manufacturer based in China, such as our company, can provide high-quality material with consistent purity and timely delivery. We are committed to supporting your research and development efforts by offering this key intermediate. When you need to buy CAS 321-17-5 for your projects, consider partnering with a supplier that guarantees quality and competitive pricing.

By understanding the diverse applications of 1-Bromo-4,5-difluoro-2-nitrobenzene, chemists and procurement specialists can better appreciate its value and strategically incorporate it into their synthesis plans.