For professionals in the chemical industry, understanding the precise properties and safe handling of raw materials is fundamental to successful operations. (Trimethylsilyl)methyl lithium, CAS 1822-00-0, is a potent organometallic reagent used across various synthetic and industrial applications. Its unique characteristics, while offering significant synthetic advantages, also necessitate careful attention to handling and storage protocols. For procurement specialists and R&D chemists, detailed knowledge of this compound is essential.

Physically, (Trimethylsilyl)methyl lithium is typically supplied as a clear to light yellow liquid. Its molecular formula is C4H11LiSi, with a molecular weight of 94.16 g/mol. A critical property is its high reactivity, particularly its sensitivity to moisture and protic solvents, indicated by a hydrolytic sensitivity rating of 8. This means it reacts rapidly with water, alcohols, and other similar compounds, often generating flammable gaseous products and requiring an inert atmosphere for storage and use.

The density is reported as approximately 0.65 g/mL at 25 °C, and it has a relatively low flash point of -49 °C, underscoring its flammability. These attributes necessitate storage under nitrogen or argon and handling in well-ventilated areas, preferably in a fume hood. Industrial users often purchase it in specialized containers designed to maintain an inert environment.

Chemically, its utility as a nucleophile in reactions like the Peterson Alkenation and as an initiator in polymerization makes it invaluable. The synthesis of α-silyl ketones and allylsilanes are common applications where its specific reactivity is leveraged.

When considering the purchase of (Trimethylsilyl)methyl lithium, it is crucial to source from reputable manufacturers and suppliers who adhere to strict quality control measures and provide comprehensive safety data. Understanding the available concentrations, solvent bases (like pentane or hexane), and packaging options is important for industrial applications. Inquiring about pricing and supply stability from multiple vendors will ensure you secure the best value and reliability for your manufacturing needs. The consistent demand for this reagent in advanced synthesis and material science makes it a strategic chemical to source effectively.