In the intricate world of pharmaceutical development and manufacturing, the quality and availability of chemical intermediates are paramount. Among these vital building blocks is 1,3-Benzenedisulfonyl Chloride, identified by its CAS number 585-47-7. This compound, a dichloride derivative of 1,3-benzenedisulfonic acid, serves as an indispensable reagent in numerous organic synthesis pathways, particularly within the pharmaceutical sector. Understanding its properties and applications is key for procurement managers and R&D scientists seeking reliable suppliers.

The Chemical Profile of 1,3-Benzenedisulfonyl Chloride

1,3-Benzenedisulfonyl Chloride typically presents as a light brown solid. Its molecular formula is C6H4Cl2O4S2, with a molecular weight of approximately 275.11 g/mol. A critical characteristic for handlers and formulators is its moisture sensitivity; it reacts with water, underscoring the importance of proper storage and handling. Its melting point range is generally between 57-60 °C, and it exhibits solubility in common organic solvents like dichloromethane and DMSO. These properties dictate its utility and the care required during its use.

Applications in Pharmaceutical Synthesis

The primary value of 1,3-Benzenedisulfonyl Chloride lies in its role as a versatile intermediate. In pharmaceutical synthesis, it is frequently employed to introduce sulfonyl groups into molecules, a common motif in many drug structures. These sulfonyl moieties can significantly influence a drug's pharmacological activity, solubility, and metabolic stability. For example, it can be used in the synthesis of sulfonamide drugs, which form a broad class of therapeutic agents, including antibiotics and diuretics. Procurement managers looking to buy 1,3-benzenedisulfonyl chloride for these applications often seek a consistent supply from a trusted manufacturer in China.

Furthermore, the compound's reactivity allows it to act as a cross-linking agent or as a precursor for more complex sulfur-containing heterocyclic compounds, which are prevalent in drug discovery. The ability to reliably source CAS 585-47-7 with high purity is essential for ensuring the reproducibility and yield of these complex synthetic steps. A reputable supplier of benzene-1,3-disulfonyl dichloride will provide detailed specifications and certificates of analysis to verify product quality.

Choosing the Right Supplier

When sourcing chemical intermediates like 1,3-Benzenedisulfonyl Chloride, partnering with a reliable supplier is crucial. Companies like NINGBO INNO PHARMCHEM, a prominent chemical manufacturer and supplier in China, offer distinct advantages. They not only provide competitive 1,3-benzenedisulfonyl chloride price China but also ensure product quality, rigorous quality control, and efficient logistics. For R&D scientists and purchasing departments, securing a consistent supply of high-quality CAS 585-47-7 from such a vendor simplifies the procurement process and mitigates risks associated with variable quality or supply chain disruptions. Investing in a reputable 1,3-benzenedisulfonyl chloride manufacturer guarantees that your pharmaceutical synthesis projects will have the foundation they need to succeed.

In conclusion, 1,3-Benzenedisulfonyl Chloride is a critical component in the pharmaceutical industry. Its unique chemical properties make it an invaluable intermediate for synthesizing a wide range of therapeutic compounds. By selecting a dependable supplier that prioritizes purity and consistent supply, businesses can confidently advance their drug development and manufacturing efforts.