Mastering Methyllithium: A Buyer's Guide for Synthesis
Methyllithium (CAS 917-54-4) stands as a pivotal organolithium reagent, indispensable for chemists engaged in sophisticated organic synthesis. Its reputation stems from its potent nucleophilic character and its capacity to act as a strong base, making it a go-to for creating carbon-carbon bonds and facilitating various transformations. For procurement managers and R&D scientists, understanding its properties and sourcing from reputable manufacturers is key.
As a primary organolithium compound, Methyllithium is the simplest example, with the empirical formula CH3Li. It exists in oligomeric forms in both solution and solid states. Due to its extreme reactivity, particularly its pyrophoric nature (igniting spontaneously in air) and vigorous reaction with water, Methyllithium is invariably supplied as a solution in ethereal solvents like diethyl ether or tetrahydrofuran. This necessitates strict anhydrous conditions and handling under an inert atmosphere, such as nitrogen or argon, to maintain its integrity and ensure safety. If you are looking to buy Methyllithium for your laboratory or industrial needs, it's crucial to partner with a reliable manufacturer.
The utility of Methyllithium in synthesis is vast. It functions as a synthetic equivalent of the methyl anion synthon, which means it can be used to introduce a methyl group onto various substrates. For instance, it reacts with ketones to yield tertiary alcohols and with non-metal halides to form methyl compounds. Its ability to react with metal halides to produce transition metal methyl compounds is also highly significant. For many R&D scientists, the primary driver for purchasing Methyllithium is its role in complex C-C bond formations, often found in the synthesis of pharmaceuticals and advanced materials.
When considering the price of Methyllithium, it's important to note that purity, concentration, and the specific solvent system will influence the cost. Bulk purchases from a direct supplier often present better value. Companies looking for Methyllithium supplier China can find several reputable sources, but due diligence regarding quality control and technical support is paramount. We offer high-purity Methyllithium solutions, ensuring that your synthetic outcomes are consistent and reliable. Our goal is to provide not just a chemical, but a solution that empowers your research.
The safe handling of pyrophoric reagents like Methyllithium cannot be overstated. Always consult the Safety Data Sheet (SDS) provided by the manufacturer. Proper personal protective equipment (PPE), including flame-resistant lab coats, safety goggles, and appropriate gloves, is essential. Reactions should be conducted in a well-ventilated fume hood, with access to appropriate fire extinguishing agents (e.g., dry chemical powder, Class D extinguisher). Understanding these safety protocols ensures that you can effectively purchase and utilize Methyllithium without incident.
In summary, Methyllithium (CAS 917-54-4) is a powerful tool in the chemist's arsenal. For those seeking to buy this reactive reagent, prioritizing a trusted manufacturer or supplier for high-purity solutions and comprehensive safety information is crucial. We are committed to providing the chemical building blocks necessary for innovation, ensuring you get the quality and support you need.
Perspectives & Insights
Molecule Vision 7
“It functions as a synthetic equivalent of the methyl anion synthon, which means it can be used to introduce a methyl group onto various substrates.”
Alpha Origin 24
“For instance, it reacts with ketones to yield tertiary alcohols and with non-metal halides to form methyl compounds.”
Future Analyst X
“Its ability to react with metal halides to produce transition metal methyl compounds is also highly significant.”