For researchers and procurement managers in the chemical and pharmaceutical sectors, accurate and sensitive detection of various analytes is paramount. Among the essential analytical tools, 2,3-Diaminonaphthalene (CAS 771-97-1), often abbreviated as DAN, stands out as a highly effective fluorometric probe, particularly for the determination of nitrite and related compounds. Understanding its properties and optimal usage can significantly enhance experimental outcomes.

The Chemistry Behind Precision: How DAN Works

2,3-Diaminonaphthalene reacts with nitrosonium ions, which are generated from nitrite under acidic conditions. This reaction leads to the formation of a highly fluorescent triazole product, 1H-naphthotriazole. This fluorescence is directly proportional to the concentration of nitrite present, making DAN an excellent reagent for quantitative analysis. The sensitivity of this method is notable, with the capability to detect nitrite concentrations as low as 10 nM. This precision makes it invaluable for scientists studying nitric oxide (NO) pathways, as NO production is closely linked to nitrite levels.

Key Applications for 2,3-Diaminonaphthalene

The primary application of DAN lies in its role as a fluorogenic probe for nitrite and nitrate measurement in biological samples. This is crucial for research in areas such as cellular signaling, inflammation, and various physiological processes where NO plays a role. Furthermore, DAN is recognized for its utility in the detection of selenium, acting as a selective colorimetric and fluorometric reagent. For laboratories seeking to buy 2,3-diaminonaphthalene for nitrite detection, sourcing from a reputable 2,3-diaminonaphthalene price china manufacturer is essential for both quality and cost-effectiveness.

Procurement Considerations for R&D and Quality Control

When sourcing chemical reagents, particularly for sensitive analytical procedures, purity and consistent supply are critical. Researchers and procurement specialists should look for suppliers that guarantee high purity, typically 99% minimum, as is standard for premium 2,3-Diaminonaphthalene. As a leading 2,3-diaminonaphthalene supplier, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing materials that meet these rigorous standards. We understand the need for reliable fluorescent reagent for selenium detection manufacturer capabilities, ensuring our clients receive products that contribute to successful research and development.

By understanding the analytical advantages and ensuring a stable supply chain, laboratories can effectively integrate 2,3-Diaminonaphthalene into their workflows. Whether for precise quantification of nitrite or for specialized selenium analysis, DAN remains a cornerstone reagent for modern chemical and biological research. To inquire about 2,3-diaminonaphthalene price or to request a sample for your critical applications, please contact us.