Mastering Organic Synthesis with Ceric Ammonium Nitrate: A Supplier's Guide
For chemists engaged in complex organic synthesis, selecting the right reagents is paramount. Ceric Ammonium Nitrate (CAN) stands out as a remarkably versatile and potent oxidizing agent. Its ability to act as a strong one-electron oxidant makes it invaluable for a myriad of transformations, from the synthesis of intricate heterocycles to the delicate deprotection of sensitive functional groups. As a leading manufacturer and supplier, we understand the critical role that high-quality CAN plays in achieving reproducible and efficient results in the laboratory and beyond.
The chemical compound, with the CAS number 16774-21-3, is characterized by its orange-red crystalline appearance and its excellent solubility in water. This makes it convenient for use in aqueous solvent mixtures, a common practice in many synthetic protocols. The [Ce(NO3)6]2- anion is the active species, providing the cerium(IV) ion (Ce4+) which readily accepts an electron, facilitating oxidative reactions and being reduced to cerium(III) (Ce3+), indicated by a color change from orange to pale yellow. This clear visual cue is a significant advantage for reaction monitoring.
One of the most celebrated applications of CAN is in organic synthesis, where it offers remarkable selectivity and high yields. It is particularly effective in oxidizing benzylic C-H bonds, alcohols, and phenols. Furthermore, its utility extends to the synthesis of important heterocycles, such as quinoxaline derivatives, which find applications in dyes, organic semiconductors, and even as DNA cleaving agents. For those looking to buy Ceric Ammonium Nitrate for these purposes, understanding its reaction profiles is key to optimizing synthetic routes.
Beyond its role as a direct oxidant, CAN also serves as an effective deprotection reagent. It is widely used to cleave para-methoxybenzyl (PMB) and 3,4-dimethoxybenzyl ethers, which are common protecting groups for alcohols. This ability to selectively remove protecting groups without damaging other parts of the molecule is a testament to its controlled reactivity. Researchers often seek a reliable supplier of Ceric Ammonium Nitrate to ensure they have access to this crucial reagent for their multi-step synthesis projects.
The industrial relevance of CAN also extends to material science. It is a key component in chrome etchants, vital materials used in the production of photomasks and liquid crystal displays. This dual role—as a fundamental synthetic tool and an industrial component—underscores the importance of a consistent and high-quality supply chain. If you are looking to purchase Ceric Ammonium Nitrate, choosing a reputable manufacturer like NINGBO INNO PHARMCHEM ensures you receive a product that meets stringent quality standards, backed by our commitment as a premier supplier in China.
Perspectives & Insights
Chem Catalyst Pro
“For those looking to buy Ceric Ammonium Nitrate for these purposes, understanding its reaction profiles is key to optimizing synthetic routes.”
Agile Thinker 7
“Beyond its role as a direct oxidant, CAN also serves as an effective deprotection reagent.”
Logic Spark 24
“It is widely used to cleave para-methoxybenzyl (PMB) and 3,4-dimethoxybenzyl ethers, which are common protecting groups for alcohols.”