In the dynamic field of organic chemistry, the selection of appropriate starting materials and intermediates is crucial for efficient and successful synthesis. NINGBO INNO PHARMCHEM CO.,LTD. is proud to be a leading provider of essential chemical building blocks, and today we are spotlighting 1-(2-Bromo-4-fluorophenyl)ethanone (CAS 1006-39-9). This compound, renowned for its versatility, serves as a cornerstone for numerous synthetic pathways in both academic research and industrial applications.

1-(2-Bromo-4-fluorophenyl)ethanone, also recognized as 2'-Bromo-4'-fluoroacetophenone, is an aromatic ketone characterized by its chemical formula C8H6BrFO. Its molecular structure features a phenyl ring substituted with a bromine atom at the ortho position and a fluorine atom at the para position, relative to an acetyl group. This specific arrangement of functional groups—the electron-withdrawing halogens and the electrophilic ketone—renders it highly reactive and amenable to a wide array of chemical transformations. It stands as a prime example of a sophisticated organic synthesis building block.

The utility of 1-(2-Bromo-4-fluorophenyl)ethanone in synthesis is manifold. For researchers in pharmaceuticals, it can be a starting point for creating novel drug candidates. For example, the bromine atom can be involved in palladium-catalyzed cross-coupling reactions, such as Suzuki-Miyaura or Sonogashira couplings, allowing for the introduction of complex aryl or alkynyl groups. The ketone functionality can be readily converted into alcohols, amines, or olefins through various reduction, reductive amination, or Wittig reactions, respectively. These are fundamental transformations in the construction of bioactive molecules.

For those looking to buy 1-(2-Bromo-4-fluorophenyl)ethanone 97% or higher purity, sourcing from reliable suppliers is key. At NINGBO INNO PHARMCHEM CO.,LTD., we understand that consistent quality is non-negotiable. Our 1-(2-Bromo-4-fluorophenyl)ethanone is rigorously tested to ensure high purity, enabling chemists to achieve predictable reaction outcomes and maximize yields. We are recognized among the premier 2'-Bromo-4'-fluoroacetophenone suppliers, dedicated to supporting the precision required in modern chemical laboratories.

The presence of fluorine in the molecule is particularly significant. Fluorine substitution is a widely employed strategy in medicinal chemistry to improve a drug's pharmacokinetic properties, such as enhanced metabolic stability, increased lipophilicity, and improved binding affinity to target enzymes or receptors. The bromine atom, on the other hand, is an excellent leaving group and a participant in many carbon-carbon bond-forming reactions, further amplifying the compound's synthetic utility.

Whether you are synthesizing complex APIs, developing advanced agrochemicals, or exploring new materials, 1-(2-Bromo-4-fluorophenyl)ethanone provides a robust platform for chemical innovation. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing researchers and industry professionals with the high-quality intermediates they need to succeed. We invite you to explore the potential of this remarkable compound in your next synthetic project.