Mastering Organic Synthesis with 2-Chloro-3-fluorobenzaldehyde
Organic synthesis is the backbone of modern chemistry, enabling the creation of novel compounds that drive innovation across industries. Among the myriad of building blocks available to chemists, fluorinated aromatic compounds hold a special place due to their unique electronic properties and biological activities. One such crucial compound is 2-Chloro-3-fluorobenzaldehyde (CAS 96516-31-3). This article aims to guide you through its key characteristics, diverse applications, and the strategic considerations for sourcing this essential chemical.
Understanding the fundamental properties of 2-Chloro-3-fluorobenzaldehyde is the first step towards its effective utilization. Typically appearing as a clear, colorless to light yellow liquid, it possesses a precise melting point range of 29-32°C and a boiling point of approximately 211.0±20.0°C. Its density is around 1.352±0.06 g/cm³. Purity levels commonly exceed 95%, with many suppliers offering grades of 98% or 99% HPLC. Storage under an inert atmosphere, such as nitrogen or argon, at 2-8°C is recommended to maintain its stability and quality. Safety data indicates it is an irritant, with hazard statements like H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Therefore, proper handling with adequate ventilation and personal protective equipment is paramount when working with this chemical intermediate.
The true value of 2-Chloro-3-fluorobenzaldehyde lies in its versatility as an intermediate in organic synthesis. The presence of an aldehyde group, a chlorine atom, and a fluorine atom on the benzene ring offers multiple reaction sites for a wide array of chemical transformations. This makes it an indispensable precursor for the synthesis of pharmaceuticals, agrochemicals, and advanced materials. For instance, it can be used in Grignard reactions, Wittig reactions, and various condensation reactions to build complex molecular architectures. Its role as a key building block in the development of novel fluorinated compounds makes it particularly attractive for researchers in medicinal chemistry and materials science, who are constantly seeking to fine-tune molecular properties.
When considering the procurement of 2-Chloro-3-fluorobenzaldehyde, understanding the market and identifying reliable suppliers is essential. Numerous manufacturers and suppliers globally offer this compound, with China being a significant source. When looking to buy 2-chloro-3-fluorobenzaldehyde, factors such as purity, price, packaging options, and delivery times should be evaluated. Many suppliers provide free samples, allowing you to verify quality before making a bulk purchase. Engaging with experienced suppliers who can provide comprehensive technical support and documentation, such as Certificates of Analysis (COA) and Material Safety Data Sheets (MSDS), is crucial for ensuring a smooth and compliant procurement process. Many online platforms offer competitive pricing for this CAS 96516-31-3 chemical intermediate, making it accessible for both research laboratories and industrial production.
In conclusion, 2-Chloro-3-fluorobenzaldehyde is a critical component for advancing chemical synthesis. Its unique structural features, coupled with its extensive applications in creating complex molecules, underscore its importance. By understanding its properties and sourcing it from reputable manufacturers, chemists can effectively leverage this versatile compound to drive innovation and achieve breakthroughs in their respective fields. Whether for academic research or industrial manufacturing, securing a dependable supply of high-quality 2-Chloro-3-fluorobenzaldehyde is key to success.
Understanding the fundamental properties of 2-Chloro-3-fluorobenzaldehyde is the first step towards its effective utilization. Typically appearing as a clear, colorless to light yellow liquid, it possesses a precise melting point range of 29-32°C and a boiling point of approximately 211.0±20.0°C. Its density is around 1.352±0.06 g/cm³. Purity levels commonly exceed 95%, with many suppliers offering grades of 98% or 99% HPLC. Storage under an inert atmosphere, such as nitrogen or argon, at 2-8°C is recommended to maintain its stability and quality. Safety data indicates it is an irritant, with hazard statements like H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Therefore, proper handling with adequate ventilation and personal protective equipment is paramount when working with this chemical intermediate.
The true value of 2-Chloro-3-fluorobenzaldehyde lies in its versatility as an intermediate in organic synthesis. The presence of an aldehyde group, a chlorine atom, and a fluorine atom on the benzene ring offers multiple reaction sites for a wide array of chemical transformations. This makes it an indispensable precursor for the synthesis of pharmaceuticals, agrochemicals, and advanced materials. For instance, it can be used in Grignard reactions, Wittig reactions, and various condensation reactions to build complex molecular architectures. Its role as a key building block in the development of novel fluorinated compounds makes it particularly attractive for researchers in medicinal chemistry and materials science, who are constantly seeking to fine-tune molecular properties.
When considering the procurement of 2-Chloro-3-fluorobenzaldehyde, understanding the market and identifying reliable suppliers is essential. Numerous manufacturers and suppliers globally offer this compound, with China being a significant source. When looking to buy 2-chloro-3-fluorobenzaldehyde, factors such as purity, price, packaging options, and delivery times should be evaluated. Many suppliers provide free samples, allowing you to verify quality before making a bulk purchase. Engaging with experienced suppliers who can provide comprehensive technical support and documentation, such as Certificates of Analysis (COA) and Material Safety Data Sheets (MSDS), is crucial for ensuring a smooth and compliant procurement process. Many online platforms offer competitive pricing for this CAS 96516-31-3 chemical intermediate, making it accessible for both research laboratories and industrial production.
In conclusion, 2-Chloro-3-fluorobenzaldehyde is a critical component for advancing chemical synthesis. Its unique structural features, coupled with its extensive applications in creating complex molecules, underscore its importance. By understanding its properties and sourcing it from reputable manufacturers, chemists can effectively leverage this versatile compound to drive innovation and achieve breakthroughs in their respective fields. Whether for academic research or industrial manufacturing, securing a dependable supply of high-quality 2-Chloro-3-fluorobenzaldehyde is key to success.
Perspectives & Insights
Alpha Spark Labs
“Therefore, proper handling with adequate ventilation and personal protective equipment is paramount when working with this chemical intermediate.”
Future Pioneer 88
“The true value of 2-Chloro-3-fluorobenzaldehyde lies in its versatility as an intermediate in organic synthesis.”
Core Explorer Pro
“The presence of an aldehyde group, a chlorine atom, and a fluorine atom on the benzene ring offers multiple reaction sites for a wide array of chemical transformations.”