Mastering Suzuki Coupling: Benefits of 3-Chlorophenylboronic Acid Pinacol Ester
For chemists in the pharmaceutical and fine chemical industries, the quest for efficient and reliable synthetic tools is paramount. Suzuki-Miyaura cross-coupling reactions have emerged as a cornerstone of modern organic synthesis, enabling the facile formation of carbon-carbon bonds. Central to the success of these reactions is the availability of high-quality boronate esters, and among them, 3-Chlorophenylboronic acid pinacol ester (CAS: 635305-47-4) stands out as a particularly valuable building block.
This compound, often referred to by its CAS number 635305-47-4, offers a unique combination of structural features that make it highly desirable for a wide array of synthetic transformations. The presence of the chlorophenyl moiety introduces specific electronic and steric influences that can be finely tuned for optimal reactivity in palladium-catalyzed cross-coupling reactions. As a leading manufacturer and supplier based in China, we understand the critical importance of consistent quality and availability for our clients who are looking to buy this essential intermediate.
The pinacol ester group provides inherent stability to the boron center, protecting it from undesirable side reactions like protodeboronation, a common challenge with free boronic acids. This stability, coupled with the compound's reactivity, makes it an excellent choice for both bench-scale research and large-scale production. When you choose to purchase 3-Chlorophenylboronic acid pinacol ester from us, you are investing in a product that has undergone rigorous quality control, ensuring high purity and batch-to-batch consistency.
The application of 3-Chlorophenylboronic acid pinacol ester in Suzuki-Miyaura couplings is extensive. It is frequently employed in the synthesis of complex pharmaceutical intermediates, agrochemicals, and advanced materials, where the precise construction of biaryl systems is crucial. The ability to reliably introduce a 3-chlorophenyl group into a molecular scaffold opens up numerous avenues for drug discovery and materials innovation. By sourcing this product, researchers and procurement managers are securing a key component that directly contributes to the efficiency and success of their synthetic endeavors.
For procurement managers seeking reliable suppliers for organic synthesis intermediates, partnering with a reputable Chinese manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. is a strategic advantage. We offer competitive pricing, ensuring that you can acquire high-purity 3-Chlorophenylboronic acid pinacol ester without compromising your budget. Our commitment extends beyond just supplying chemicals; we aim to be a trusted partner in your R&D and manufacturing processes, providing the materials you need to achieve your goals. If you are looking to buy this critical intermediate, consider our offerings and experience the benefits of quality, reliability, and competitive pricing.
Perspectives & Insights
Logic Thinker AI
“It is frequently employed in the synthesis of complex pharmaceutical intermediates, agrochemicals, and advanced materials, where the precise construction of biaryl systems is crucial.”
Molecule Spark 2025
“The ability to reliably introduce a 3-chlorophenyl group into a molecular scaffold opens up numerous avenues for drug discovery and materials innovation.”
Alpha Pioneer 01
“By sourcing this product, researchers and procurement managers are securing a key component that directly contributes to the efficiency and success of their synthetic endeavors.”