Maximizing API Solubility: A Guide to 2,6-Di-O-methyl-beta-cyclodextrin
For pharmaceutical researchers and product formulators, achieving optimal solubility for Active Pharmaceutical Ingredients (APIs) is a persistent challenge. Many promising drug candidates suffer from poor aqueous solubility, directly impacting their bioavailability, efficacy, and ultimately, their therapeutic potential. This is where advanced excipients like 2,6-Di-O-methyl-beta-cyclodextrin (CAS 51166-71-3) play a pivotal role.
As a leading supplier of specialty chemicals, NINGBO INNO PHARMCHEM CO.,LTD. understands the critical need for high-quality materials that can solve complex formulation problems. 2,6-Di-O-methyl-beta-cyclodextrin is a chemically modified cyclic oligosaccharide renowned for its unique structure. Composed of seven glucose units, it features a hydrophilic exterior and a lipophilic internal cavity. This amphiphilic nature allows it to encapsulate hydrophobic molecules, effectively forming 'inclusion complexes'.
The primary advantage of using 2,6-Di-O-methyl-beta-cyclodextrin is its remarkable ability to increase the solubility of poorly water-soluble drugs. By forming a complex, the cyclodextrin shields the hydrophobic API from the aqueous environment, facilitating its dissolution and absorption in the body. This enhancement in solubility can lead to improved pharmacokinetic profiles, potentially allowing for lower dosages, reduced side effects, and greater patient compliance. If you are looking to buy pharmaceutical-grade cyclodextrins, our product offers superior purity and performance.
Beyond solubility enhancement, this cyclodextrin derivative also offers significant benefits in terms of stability. It can protect sensitive APIs from hydrolysis, oxidation, or photodegradation, extending the shelf-life of the final drug product. Furthermore, it can mask unpleasant tastes or odors, a crucial consideration for oral dosage forms.
NINGBO INNO PHARMCHEM CO.,LTD., as a dedicated manufacturer based in China, is committed to providing a consistent supply of 2,6-Di-O-methyl-beta-cyclodextrin that meets stringent quality standards. Our product boasts an assay of ≥98%, ensuring that you receive a reliable and effective material for your research and development needs. We are dedicated to supporting the pharmaceutical industry with innovative excipients.
For those seeking to source high-performance cyclodextrins, understanding the price and availability is key. We encourage you to contact NINGBO INNO PHARMCHEM CO.,LTD. for a competitive quote and to discuss your specific requirements. Whether you are in early-stage research or scaling up production, our team is ready to assist you in leveraging the benefits of 2,6-Di-O-methyl-beta-cyclodextrin for your next pharmaceutical breakthrough.
Perspectives & Insights
Chem Catalyst Pro
“We are dedicated to supporting the pharmaceutical industry with innovative excipients.”
Agile Thinker 7
“For those seeking to source high-performance cyclodextrins, understanding the price and availability is key.”
Logic Spark 24
“Whether you are in early-stage research or scaling up production, our team is ready to assist you in leveraging the benefits of 2,6-Di-O-methyl-beta-cyclodextrin for your next pharmaceutical breakthrough.”