Merrifield resin, identified by its CAS number 55844-94-5, is a pivotal component in various chemical synthesis applications, most notably in solid-phase peptide synthesis. This chloromethylated polystyrene bead offers a unique combination of chemical stability and reactive functionality, making it an indispensable tool for researchers and chemical manufacturers. As a dedicated manufacturer and supplier in China, we are committed to providing high-quality Merrifield Resin with precise specifications that meet the rigorous demands of modern chemical processes. Understanding its properties is key to unlocking its full potential in your projects.

The chemical structure of Merrifield resin is based on a cross-linked polystyrene matrix. The chloromethyl groups (-CH2Cl) are the primary reactive sites, typically introduced through a post-polymerization reaction. This functionalization allows for the covalent attachment of molecules, such as the first amino acid in peptide synthesis. The degree of cross-linking, usually with divinylbenzene, impacts the swelling characteristics of the resin in various solvents, affecting reaction rates and accessibility of the reactive sites. Typical specifications include particle size distribution (e.g., 100-200 mesh or 200-400 mesh) and substitution levels, often expressed in millimoles of functional groups per gram of resin (e.g., 0.3-1.0 mmol/g or higher).

The performance of Merrifield resin is highly dependent on its purity and consistent functionalization. As a trusted supplier, we ensure that our product is characterized by its white polymer bead appearance and high purity, minimizing potential interference with sensitive chemical reactions. Whether you are employing the Boc strategy for peptide synthesis or exploring other applications in organic chemistry, such as solid-phase synthesis of small molecules or combinatorial chemistry, the reliability of your starting materials is crucial. When you choose to buy Merrifield Resin from us, you are assured of a product that adheres to strict quality control protocols.

For businesses and research institutions, sourcing chemical intermediates like Merrifield Resin from an experienced manufacturer in China offers significant advantages in terms of both cost and accessibility. We provide detailed technical data and certificates of analysis to support your quality assurance processes. Our aim is to be your preferred partner for high-quality chemical supplies, offering competitive prices and dependable delivery. If your work requires high-performance Merrifield Resin, we encourage you to purchase from our extensive inventory. Contact us to learn more about our specifications and how we can support your synthesis needs.