Methanol-D4 (CAS 811-98-3) is more than just a chemical compound; it's an enabler of precision in scientific discovery. As a deuterated analog of methanol, its unique isotopic composition makes it an indispensable tool, particularly in the field of Nuclear Magnetic Resonance (NMR) spectroscopy. For researchers and procurement managers seeking to buy Methanol-D4, a thorough understanding of its properties and applications is crucial.

At its core, Methanol-D4 is methanol where the four hydrogen atoms are replaced by deuterium. This isotopic substitution profoundly impacts its interaction with electromagnetic radiation in NMR experiments. Regular methanol contains protium (¹H), which has a strong NMR signal that can interfere with the analysis of a sample dissolved in it. Deuterium (²H), however, has a different NMR frequency and a lower gyromagnetic ratio, meaning its signal in a ¹H NMR spectrum is negligible. This allows researchers to obtain cleaner spectra, facilitating the precise identification of molecular structures and the study of chemical reactions without solvent interference.

Key physical properties of Methanol-D4 include its colorless liquid appearance, a boiling point of approximately 65.4 °C, and a density of around 0.888 g/mL at 25 °C. These properties are consistent with its non-deuterated counterpart, but its value lies in its deuteration. The purity of Methanol-D4 is typically specified by its isotopic enrichment, with grades commonly available at 99.8 atom % D or even higher. This high level of enrichment is vital for achieving optimal results in sensitive analytical techniques.

The primary application of Methanol-D4 is undoubtedly as an NMR solvent. It is favored in scenarios where the solvent's proton signals would otherwise obscure the spectral data of the compound under investigation. This makes it a standard reagent in academic research, pharmaceutical development, and advanced materials science. Beyond NMR, it can also serve as a reference standard or a solvent in other spectroscopic techniques where minimizing proton signals is advantageous.

When sourcing Methanol-D4, identifying a reliable supplier is paramount. We understand the importance of consistent quality and prompt delivery. Whether you require small quantities for specific experiments or bulk orders for industrial processes, ensuring you buy Methanol-D4 from a trusted manufacturer guarantees the purity and isotopic enrichment necessary for accurate scientific outcomes. Exploring options from established chemical suppliers ensures you receive a product that meets the demanding requirements of modern analytical chemistry.