As the chemical industry continues to innovate, the demand for specialized building blocks that enable the creation of advanced molecules grows. Methyl 3,3,3-Trifluoropropionate (CAS 18830-44-9) has emerged as a highly versatile fluorinated intermediate, prized for the unique characteristics its trifluoromethyl group imparts to synthesized compounds. For chemists and procurement specialists, understanding the properties and applications of this compound is key to unlocking its potential in various synthetic pathways.

Methyl 3,3,3-Trifluoropropionate is a clear, colorless liquid with a molecular formula of C4H5F3O2 and a molecular weight of approximately 142.08 g/mol. Its defining feature is the –CF3 group attached to the propionate ester backbone. This highly electronegative group significantly influences the reactivity and physical properties of the molecule and any subsequent derivatives. Its boiling point is around 96°C, and it is typically supplied with a purity of ≥98.0% (GC), making it suitable for demanding synthetic applications where precision is crucial.

The versatility of Methyl 3,3,3-Trifluoropropionate stems from its ability to act as a source of the trifluoromethyl moiety or as a building block in ester-based reactions. In pharmaceutical research, it is frequently employed in the synthesis of APIs where the trifluoromethyl group can enhance lipophilicity, improve metabolic stability, and increase binding affinity to biological targets. This leads to the development of more effective and longer-lasting drug molecules. Researchers looking to buy this compound often cite its utility in creating novel drug candidates with improved pharmacological profiles.

In the agrochemical sector, the incorporation of fluorine, often facilitated by intermediates like Methyl 3,3,3-Trifluoropropionate, can lead to pesticides and herbicides with enhanced potency, selectivity, and environmental persistence. The trifluoromethyl group can alter the mode of action and metabolic pathways of these crop protection agents, contributing to more efficient and targeted pest control. Sourcing this key intermediate from reliable manufacturers ensures that agrochemical companies can drive innovation in their product lines.

Furthermore, the material science field utilizes this fluorinated ester in the creation of specialty polymers and functional materials. The inherent properties conferred by fluorine—such as thermal stability, chemical resistance, and low surface energy—make these materials suitable for high-performance applications. Whether used as a monomer or as a reagent in surface modification, Methyl 3,3,3-Trifluoropropionate offers a pathway to advanced material design.

As a leading supplier, we recognize the growing importance of versatile fluorinated building blocks. We are committed to providing high-quality Methyl 3,3,3-Trifluoropropionate to researchers and manufacturers globally. If you are interested in exploring its synthetic potential or need to secure a reliable supply, we encourage you to contact us for pricing and technical information. Partner with us to access this valuable intermediate and advance your chemical synthesis projects.