The field of porous materials has been revolutionized by the advent of Metal-Organic Frameworks (MOFs), crystalline structures composed of metal ions coordinated to organic ligands. These materials possess exceptionally high surface areas and tunable pore sizes, making them attractive for a wide array of applications, from gas storage and catalysis to sensing and drug delivery. At the heart of MOF synthesis lies the selection of appropriate organic linkers. Among the diverse range of linkers available, 2-Azidoterephthalic Acid (CAS 3600-74-6) has emerged as a particularly valuable compound. As a dedicated supplier of fine chemicals, we are pleased to provide insights into this critical molecule and how researchers can effectively source it for their synthetic endeavors.

The Chemistry of 2-Azidoterephthalic Acid in MOF Construction

2-Azidoterephthalic Acid, chemically known as 2-azido-1,4-benzenedicarboxylic acid, is a derivative of terephthalic acid. Its molecular structure features a benzene ring substituted with two carboxylic acid groups at the 1 and 4 positions, and an azide group (-N3) at the 2 position. The two carboxylic acid groups are key to its function as a linker; they readily deprotonate to form carboxylate anions, which then coordinate with metal ions or clusters, acting as nodes in the MOF structure. This coordination leads to the formation of extended, three-dimensional networks.

The presence of the azide group is what sets 2-Azidoterephthalic Acid apart. This functional group can influence the electronic properties of the MOF and can also be a site for further chemical modification through click chemistry or other azide reactions. This capability allows for the fine-tuning of MOF properties, such as guest molecule adsorption or catalytic activity, after the framework has been assembled. For researchers aiming to buy 2-azidoterephthalic acid, understanding these chemical nuances is crucial for designing MOFs with specific functionalities.

Properties and Sourcing Considerations

When engaging in MOF synthesis, the purity and consistency of the organic linker are paramount. 2-Azidoterephthalic Acid is typically supplied as an earthy yellow powder with a reported purity of 95% or higher. It exhibits good solubility in common polar aprotic solvents like DMF and DMSO, which are frequently used in MOF synthesis protocols, particularly solvothermal methods. Proper storage, usually in a cool, dry place and sealed to prevent degradation, is recommended to maintain its quality. For professionals seeking to purchase this compound, selecting a supplier that emphasizes stringent quality control and provides detailed product specifications is essential. We, as a manufacturer and supplier, ensure our 2-Azidoterephthalic Acid meets these high standards, offering it in various package sizes to suit research needs, from grams to kilograms.

The ability to reliably obtain specialized chemicals like 2-Azidoterephthalic Acid is a cornerstone of progress in material science. Our role as a supplier is to bridge the gap between synthesis needs and product availability. We encourage researchers and developers to inquire about our pricing for bulk orders and to leverage our expertise in providing high-quality chemical intermediates. By sourcing from a trusted manufacturer, you streamline your research process and enhance the likelihood of successfully synthesizing novel MOF structures with your desired properties.