For researchers and product developers in the chemical and pharmaceutical industries, understanding the versatility of key intermediates is crucial for innovation. N-Butyl Cyanoacetate (CAS 5459-58-5) exemplifies this, serving as a highly adaptable active methylene reagent in modern organic synthesis. NINGBO INNO PHARMCHEM CO.,LTD., a leading manufacturer and supplier in China, provides high-quality N-Butyl Cyanoacetate that empowers a wide range of synthetic applications. We are your trusted source to buy this essential compound and explore its capabilities.

The core utility of N-Butyl Cyanoacetate lies in its reactive methylene group, positioned between two electron-withdrawing groups (a nitrile and an ester). This structural feature makes the alpha-hydrogens highly acidic, allowing for easy deprotonation to form a stable carbanion. This carbanion is a potent nucleophile, readily participating in various carbon-carbon bond-forming reactions. As a leading supplier, we ensure our N-Butyl Cyanoacetate is of the purity required for these sensitive transformations.

One of the most significant applications is in alkylation reactions. The N-Butyl Cyanoacetate carbanion can be alkylated with various alkyl halides or tosylates, introducing new carbon chains. This is a fundamental step in building more complex molecular architectures. Similarly, it participates effectively in acylation reactions, allowing for the introduction of carbonyl functionalities. These reactions are vital when developing novel drug candidates or advanced materials.

Furthermore, N-Butyl Cyanoacetate is a key component in condensation reactions, particularly the Knoevenagel condensation, where it reacts with aldehydes and ketones. This reaction yields α,β-unsaturated cyanoesters, which are themselves valuable synthetic intermediates. The ability to control stereochemistry and regiochemistry in these reactions makes N-Butyl Cyanoacetate a powerful tool for chemists. When you purchase N-Butyl Cyanoacetate from a reputable manufacturer like us, you gain access to a reagent that enhances reaction efficiency.

The impact of N-Butyl Cyanoacetate extends to the pharmaceutical sector, where it's used in the synthesis of various active pharmaceutical ingredients (APIs) and their precursors. In agrochemicals, it serves as a building block for pesticides and herbicides. Its versatility also finds application in the production of dyes, polymers, and specialty fine chemicals. For companies looking to source this compound, understanding its broad applicability makes it a strategic purchase.

NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to being your premier N-Butyl Cyanoacetate supplier in China. We offer our product for sale, ensuring competitive pricing and reliable availability. We invite you to reach out to us for a quote and to discuss how our high-quality N-Butyl Cyanoacetate can be integrated into your synthetic strategies. Partner with us to unlock the full potential of this versatile chemical intermediate.