Electrophoresis is a fundamental technique in molecular biology and biochemistry, enabling the separation of biomolecules based on their size, charge, or shape. The efficiency and accuracy of these separations are heavily influenced by the buffer system used. N-Carbamoylmethyltaurine, commonly known as ACES (CAS 7365-82-4), is a zwitterionic buffer that offers significant advantages in various electrophoresis applications.

As a premium supplier of research chemicals, we recognize the critical role buffers play in achieving reproducible and precise results. ACES, with its pKa of approximately 6.8, provides excellent buffering capacity in the pH range of 6.1 to 7.5. This range is often ideal for maintaining the native state of proteins and nucleic acids during electrophoresis, preventing denaturation and ensuring accurate separation profiles.

One of the key benefits of using ACES in electrophoresis is its high purity. Our ACES products, typically exceeding 97.0% purity, are manufactured to the highest standards, minimizing the presence of ions or contaminants that could interfere with the electrical field or the separation process itself. This is particularly important in techniques like isoelectric focusing of proteins, where precise pH gradients are essential.

When used in polyacrylamide gel electrophoresis (PAGE) or agarose gel electrophoresis, ACES helps maintain a stable pH throughout the gel and running buffer. This stability is crucial for consistent migration of DNA, RNA, or protein samples. Unlike some other buffers, ACES exhibits less complexation with metal ions, which can be beneficial in systems where metal ions might influence protein folding or enzyme activity during the run.

For laboratories focused on protein analysis, ACES can be an excellent choice for maintaining the correct pH for isoelectric focusing (IEF) or for use in buffer systems for native PAGE. Its buffering range allows for fine-tuning of the environment to optimize protein separation based on their isoelectric points.

As a dedicated manufacturer and supplier of ACES in China, we are committed to providing researchers with the quality reagents they need. If you are looking to buy ACES for your electrophoresis applications, our products offer the purity and performance required for demanding analytical techniques. We ensure a stable supply chain, allowing you to procure this vital buffer with confidence.

In conclusion, N-Carbamoylmethyltaurine (ACES) is a highly effective buffer for electrophoresis and related techniques. Its favorable pH range, high purity, and zwitterionic nature make it a reliable choice for researchers aiming for precision and accuracy. We encourage you to consider our high-quality ACES for your next project and to contact us for a quote to purchase this essential laboratory chemical.