For chemists engaged in organic synthesis, the availability of reliable and high-quality intermediates is the bedrock of successful research and development. N-Isopropyl-4-nitroaniline (CAS 25186-43-0) stands out as a valuable building block, enabling the creation of complex molecules for diverse applications. This article aims to provide R&D scientists with practical insights into the synthesis, handling, and application of this crucial compound from the perspective of an experienced chemical supplier.

Synthesis and Properties of N-Isopropyl-4-nitroaniline

N-Isopropyl-4-nitroaniline, with the molecular formula C9H12N2O2, is typically synthesized through established chemical pathways. While specific synthesis routes may vary, the resulting product is characterized by its light yellow to green-yellow solid form and a high purity level, often specified at 98.5% MIN. Understanding its properties, such as melting point, boiling point, and solubility, is critical for effective laboratory handling and reaction design. For instance, knowledge of its stability and potential incompatibilities is essential for safe storage and use.

Handling and Safety Considerations

As with any chemical intermediate, safe handling practices are paramount when working with N-Isopropyl-4-nitroaniline. Always consult the Material Safety Data Sheet (MSDS) or Safety Data Sheet (SDS) provided by the manufacturer. Key safety precautions generally include:

  • Personal Protective Equipment (PPE): Wearing appropriate gloves, eye protection (safety goggles or face shield), and lab coats is essential.
  • Ventilation: Work in a well-ventilated area or under a fume hood to minimize inhalation exposure.
  • Storage: Store in a cool, dry place, away from incompatible materials, and protected from light and moisture as recommended by the supplier. Typical storage conditions might be around 2-8°C.
  • Disposal: Follow local regulations for the safe disposal of chemical waste.

Applications in R&D and Beyond

The utility of N-Isopropyl-4-nitroaniline extends to several key areas:

  • Pharmaceutical Synthesis: It serves as a precursor in the development of various drug candidates and active pharmaceutical ingredients (APIs), contributing unique structural elements to medicinal compounds. Researchers looking to buy N-Isopropyl-4-nitroaniline for drug discovery will value its reliable purity.
  • Agrochemical Development: This intermediate is also critical for synthesizing new generations of herbicides, insecticides, and fungicides, playing a role in agricultural innovation.
  • Materials Science: Its properties may also be leveraged in the creation of specialized polymers, dyes, or other advanced materials.

Procuring from a Trusted Supplier

When sourcing N-Isopropyl-4-nitroaniline (CAS 25186-43-0), R&D scientists should prioritize suppliers who can consistently deliver high-purity material along with comprehensive technical data. Direct inquiries to established suppliers in China, such as those offering competitive pricing and reliable logistics, are recommended. Access to detailed product specifications and prompt responses to inquiries are hallmarks of a dependable chemical partner.

In summary, N-Isopropyl-4-nitroaniline (CAS 25186-43-0) is an indispensable tool for modern organic synthesis. By adhering to safe handling practices and partnering with quality-focused suppliers, researchers can effectively utilize this intermediate to drive innovation in pharmaceuticals, agrochemicals, and beyond.