For professionals in the chemical industry, a thorough understanding of technical specifications is crucial when selecting and utilizing chemical intermediates. This article provides a detailed technical examination of 4,4'-(1H-1,2,4-Triazole-3,5-diyl)dipyridine (CAS 4329-78-6), addressing its nomenclature, synthesis challenges, and providing answers to common technical inquiries faced by researchers and procurement specialists looking to buy this compound.

The systematic nomenclature of this compound, such as 4-[5-(4-pyridinyl)-1H-1,2,4-triazol-3-yl]pyridine, clearly delineates its structure, featuring a 1,2,4-triazole core linked to two pyridine rings at their 4-positions. Commonly known synonyms like 3,5-dipyridyl-1,2,4-triazole further aid in its identification. Its molecular formula is C12H9N5, with a molecular weight of 223.23 g/mol. The compound is typically supplied as a yellow or off-white solid, with a high melting point indicative of its stable, planar structure.

Technical challenges in the synthesis of 4,4'-(1H-1,2,4-Triazole-3,5-diyl)dipyridine often revolve around achieving high yields and purity. Reactions may involve sensitive intermediates or require precise control over reaction conditions. For instance, cyclocondensation and oxidative cyclization steps need careful optimization to prevent side reactions such as over-oxidation or incomplete ring closure. Purification methods, commonly chromatography on silica gel, are critical for isolating the pure product, which can impact the overall yield. Manufacturers continually refine these processes to improve efficiency and cost-effectiveness for purchasers.

From a research perspective, understanding the compound's behavior in various applications is key. For example, in MOF synthesis, the exact crystallographic arrangement of the ligand and metal ions can be complex. Researchers often face challenges with structural refinement due to potential disorder in the triazole-pyridine moiety. Computational methods, such as Density Functional Theory (DFT), are increasingly used to predict reactivity and guide experimental design in catalytic MOFs. These advanced studies highlight the intricate nature of utilizing such compounds effectively.

When considering a purchase, technical questions often arise regarding synthetic routes, yield optimization, and characterization data. For example, discrepancies in reported synthesis yields can be attributed to variations in reagents, catalysts, and purification protocols. Addressing these questions is part of our commitment as a reliable chemical supplier. We ensure that our product is thoroughly characterized using established spectroscopic techniques, and we are prepared to provide detailed technical information to support your purchasing decisions. By choosing a trusted manufacturer in China, you gain access to high-quality intermediates like 4,4'-(1H-1,2,4-Triazole-3,5-diyl)dipyridine, backed by solid technical expertise and a commitment to product excellence.