N-Bromosuccinimide (NBS), identified by CAS 128-08-5, is a chemical reagent celebrated for its versatility and selective reactivity in organic synthesis. While its fame in allylic and benzylic bromination via radical pathways is well-established, its utility extends to a variety of other critical chemical transformations. For scientists and procurement specialists, understanding the full spectrum of NBS applications and ensuring a reliable supply chain is paramount. As a leading manufacturer and supplier, we provide high-purity NBS to meet diverse industrial and research needs.

Beyond its role in radical substitution, NBS is a valuable reagent for electrophilic addition reactions. For instance, it reacts with alkenes in aqueous solvents to yield bromohydrins, which are bifunctional compounds useful in subsequent synthetic steps. This pathway offers a controlled method for introducing both bromine and a hydroxyl group across a double bond, following Markovnikov's rule with anti-stereoselectivity. This makes NBS an excellent choice for creating chiral building blocks or introducing necessary functionalities.

Another significant application of NBS is in the synthesis of alpha-bromo carbonyl compounds. This bromination can occur via acid catalysis or radical pathways and yields intermediates that are highly reactive in carbon-carbon bond forming reactions, such as alkylations or Wittig reactions. Furthermore, NBS is a key component in the Hofmann rearrangement, a process that converts primary amides into primary amines with the loss of a carbonyl carbon. This reaction is vital for synthesizing amine-containing molecules, common in pharmaceuticals and specialty chemicals.

For businesses requiring N-Bromosuccinimide, partnering with a reputable manufacturer is essential for consistent quality and supply. We offer NBS with a guaranteed minimum assay of 99.5%, ensuring its suitability for demanding chemical processes. Our commitment extends to providing competitive pricing and convenient online purchasing options, making it straightforward to buy N-Bromosuccinimide. We aim to be your trusted partner for all your NBS requirements.

In summary, N-Bromosuccinimide is a powerful and adaptable reagent with applications ranging from radical bromination to electrophilic additions and rearrangement reactions. Its broad utility makes it a staple in many chemical sectors. We invite you to explore our comprehensive range of NBS products and experience the advantages of sourcing from a reliable manufacturer. Contact us today for inquiries and quotes on high-quality NBS for your chemical needs.