N,N-Diethyl-m-toluidine: Properties and Key Chemical Synthesis Applications
For chemists engaged in organic synthesis, understanding the reactivity and utility of various chemical compounds is fundamental to innovation. N,N-Diethyl-m-toluidine (CAS 91-67-8) is a prime example of a versatile aromatic amine that finds extensive application as a reagent and intermediate in numerous synthetic pathways. As a key chemical synthesis intermediate, its properties make it invaluable for creating complex molecules across various industries.
N,N-Diethyl-m-toluidine is characterized by its liquid form, typically appearing as a light orange to yellow or green clear liquid, with a reported melting point around 46.25°C (estimated) and a boiling point of 97°C at 17 mmHg. Its refractive index is approximately 1.535-1.537, and it has a density of around 0.92. These physical properties, coupled with its chemical structure—a tertiary amine with a methyl group on the benzene ring—dictate its reactivity. The nitrogen atom's lone pair makes it nucleophilic, while the aromatic ring can undergo electrophilic aromatic substitution.
In organic synthesis, N,N-Diethyl-m-toluidine is often employed for its ability to act as a base or a nucleophile. It is particularly useful in reactions requiring a moderately sterically hindered tertiary amine, such as in certain condensation reactions or as a catalyst scavenger. Its role as a building block is significant in the synthesis of dyes and pigments, where its structure contributes to chromophoric systems. Furthermore, it serves as an intermediate in the preparation of more complex organic molecules relevant to pharmaceuticals and agrochemicals.
Researchers looking to buy N,N-Diethyl-m-toluidine for their synthetic endeavors will benefit from sourcing from a reliable manufacturer. The purity of the compound is critical for achieving high yields and desired stereochemistry in complex reactions. When you seek to purchase N,N-Diethyl-m-toluidine, ensure your supplier can provide consistent quality and adequate technical support. Exploring options from experienced chemical companies, particularly those with a strong presence as a manufacturer in China, can offer access to competitive pricing and a stable supply.
The strategic use of N,N-Diethyl-m-toluidine can significantly enhance the efficiency and scope of your chemical synthesis projects. Its well-defined properties and reactivity make it a reliable choice for chemists aiming to develop novel compounds or optimize existing synthetic routes. By prioritizing quality and working with reputable suppliers, you can harness the full potential of this important chemical intermediate.
Perspectives & Insights
Silicon Analyst 88
“In organic synthesis, N,N-Diethyl-m-toluidine is often employed for its ability to act as a base or a nucleophile.”
Quantum Seeker Pro
“It is particularly useful in reactions requiring a moderately sterically hindered tertiary amine, such as in certain condensation reactions or as a catalyst scavenger.”
Bio Reader 7
“Its role as a building block is significant in the synthesis of dyes and pigments, where its structure contributes to chromophoric systems.”