Nonafluorobutyl Bromide (CAS 375-48-4) is a significant compound within the realm of fluorinated chemicals, prized for its unique physical and chemical properties that make it valuable across several industrial sectors. As a perfluorinated organic molecule, its structure dictates its stability and reactivity, positioning it as a critical intermediate for researchers and manufacturers alike. Understanding these attributes is key to leveraging its full potential.

Key Physical and Chemical Properties

Nonafluorobutyl Bromide, also known by synonyms such as 1-Bromononafluorobutane or Perfluorobutyl bromide, possesses a molecular formula of C4BrF9 and a molecular weight of approximately 298.93 g/mol. Its most notable physical characteristic is its clear liquid form at room temperature. Key properties include:

  • Boiling Point: Typically around 43-44°C, indicating relatively low volatility for a brominated fluorocarbon.
  • Density: Approximately 1.904 g/cm³ at 20°C, making it a dense liquid.
  • Stability: Due to the strong carbon-fluorine bonds, it exhibits high thermal and chemical stability, resisting degradation under many harsh conditions.
  • Solubility: It is generally poorly soluble in polar solvents but can dissolve nonpolar compounds. Its hydrophobic nature is a characteristic feature of perfluorinated substances.
  • Reactivity: While stable, the bromine atom provides a reactive site for various chemical transformations, allowing it to be used as a building block in organic synthesis.

Industrial Applications and Significance

The unique combination of properties makes Nonafluorobutyl Bromide an indispensable reagent in several key industries:

1. Manufacturing of New Materials: It serves as a crucial intermediate in the production of advanced fluorinated polymers, coatings, and surface treatments. These materials are known for their exceptional resistance to heat, chemicals, and weathering, finding applications in electronics, automotive, and aerospace industries.

2. Pharmaceutical Research and Development: The introduction of perfluorinated alkyl chains can significantly influence the lipophilicity, metabolic stability, and bioavailability of pharmaceutical compounds. Nonafluorobutyl Bromide acts as a valuable building block for synthesizing fluorinated pharmaceutical intermediates and active pharmaceutical ingredients (APIs).

3. Agrochemical Sector: In the development of new pesticides and herbicides, fluorination can enhance biological activity and persistence. Nonafluorobutyl Bromide is utilized in the synthesis of novel agrochemicals designed for improved crop protection.

4. Specialty Chemical Synthesis: As a versatile reagent, it participates in various organic reactions, enabling the creation of complex fluorinated molecules and specialty chemicals used in diverse applications.

Sourcing Nonafluorobutyl Bromide

For industries requiring this specialized chemical, reliable sourcing is essential. Manufacturers and suppliers often provide Nonafluorobutyl Bromide with specified purities, typically greater than 97%. Key considerations for buyers include ensuring a stable supply, competitive pricing, and access to essential documentation like Safety Data Sheets (SDS) and Certificates of Analysis (COA). Partnering with a dedicated manufacturer, especially those in China, can offer advantages in terms of both cost and product availability.

In summary, Nonafluorobutyl Bromide stands out due to its inherent stability and its utility as a versatile synthetic intermediate. Its continued application in advanced materials, pharmaceuticals, and agrochemicals underscores its importance in modern chemical innovation.