In the dynamic field of biochemical research and development, the precise control of reaction environments is non-negotiable. Among the most critical environmental factors is pH, which can profoundly influence the outcome of enzymatic reactions, protein folding, and molecular interactions. This is precisely where the exceptional properties of Bicine, a zwitterionic buffer, come into play, offering researchers a reliable tool for optimizing their experiments. As a leading manufacturer and supplier, we are dedicated to providing scientists with high-purity Bicine to meet these exacting demands.

Bicine, identified by CAS number 150-25-4, is a cornerstone in the toolkit of many biochemists due to its robust buffering capacity within the alkaline pH range, typically between 7.6 and 9.0. This makes it an ideal choice for a wide array of biochemical applications, particularly those involving enzymes that function optimally in this pH spectrum, or for research conducted at reduced temperatures where pH stability is paramount. The inherent chemical stability of Bicine ensures that it maintains its buffering efficacy throughout extended experimental periods, a critical factor for complex assays or low-temperature incubations. Researchers looking to buy Bicine often seek these stability advantages.

One of the key distinctions of Bicine, and indeed of many Good's buffers, is its low tendency to chelate metal ions. This characteristic is vital in biochemical studies where metal ions may be present as cofactors for enzymes or as components of reagents. By minimizing unwanted interactions with these metal ions, Bicine helps prevent confounding effects, ensuring that observed experimental results are truly attributable to the biological system under investigation, rather than to buffer interference. This makes it a preferred buffer for studies involving metalloenzymes or metal-catalyzed reactions.

The applications of Bicine are diverse and far-reaching. It is widely employed in protein purification, including ion exchange chromatography, where its consistent buffering maintains the necessary ionic environment for separation. It also plays a role in preparing stable substrate solutions for diagnostic assays, such as the determination of serum guanase levels, contributing to accurate diagnostic results. Furthermore, Bicine is a valuable buffer in techniques like SDS-PAGE for protein separation and in studies of peptide and protein crystallization. For scientific institutions and companies, sourcing high-quality Bicine from a reliable Bicine supplier ensures that these critical applications proceed without interruption.

When considering the procurement of Bicine, understanding the importance of purity cannot be overstated. Our commitment as a manufacturer is to provide Bicine with a purity of ≥99%, guaranteeing minimal impurities that could interfere with sensitive biochemical processes. We offer Bicine at competitive prices, and encourage inquiries for bulk purchases, recognizing the need for cost-effectiveness in research and development. Whether you are scaling up a bioprocess or conducting fundamental research, our Bicine is formulated to deliver the performance and reliability you require. Contact us to discuss your specific Bicine needs and to obtain a quote; we are your trusted partner for high-quality biochemical reagents.