Organic synthesis is the cornerstone of many modern industries, from pharmaceuticals and agrochemicals to materials science and advanced polymers. Within this vast field, specific chemical intermediates offer unique reactivity and versatility, enabling chemists to construct complex molecules efficiently. Cinnamyl Acetoacetate (CAS 57582-46-4), a compound with a reactive acetoacetate moiety and a cinnamylic group, presents an excellent opportunity for innovative synthetic strategies. As a dedicated supplier of fine chemicals, we are pleased to explore its potential in various organic synthesis applications.

The Chemical Versatility of Cinnamyl Acetoacetate

Cinnamyl Acetoacetate, a light brown liquid, possesses two key functional groups that contribute to its synthetic utility:

  • Acetoacetate Moiety: The β-keto ester functionality is highly versatile. The alpha-hydrogens are acidic and can be readily deprotonated to form an enolate, which is a potent nucleophile. This allows for a wide range of carbon-carbon bond-forming reactions, such as alkylation, acylation, and Michael additions. The ester can also undergo transesterification, hydrolysis, and decarboxylation under various conditions, providing pathways to diverse carbonyl compounds and carboxylic acids.
  • Cinnamylic Group: The presence of a double bond conjugated with an aromatic ring (phenyl group) offers opportunities for addition reactions, epoxidation, and as a site for further functionalization. The allylic nature of the ester linkage can also influence reactivity.

This combination of reactive sites makes Cinnamyl Acetoacetate a valuable building block for creating diverse organic structures.

Applications in Organic Synthesis

The inherent reactivity of Cinnamyl Acetoacetate allows its application in several synthetic pathways:

  • Synthesis of Heterocycles: The β-keto ester can participate in condensation reactions with amines, hydrazines, or other nucleophiles to form various heterocyclic compounds, which are prevalent in pharmaceuticals and agrochemicals.
  • Carbon Chain Elongation: Through enolate chemistry, chemists can extend carbon chains, introducing the cinnamyl-acetoacetate fragment into larger molecules. This is particularly useful for building precursors to complex natural products or custom-designed molecules.
  • Flavor and Fragrance Precursors: As noted for its direct use, Cinnamyl Acetoacetate can also serve as a precursor to other specialty aroma chemicals through controlled chemical modifications.
  • Pharmaceutical Intermediate Synthesis: Beyond Cilnidipine, its structure might lend itself to the synthesis of other drug candidates or intermediates where similar structural motifs are required.

Sourcing for Research and Development

For researchers and development chemists looking to buy Cinnamyl Acetoacetate, ensuring access to consistent quality and reliable supply is crucial. As a prominent Cinnamyl Acetoacetate manufacturer and supplier in China, we offer this compound to support your laboratory needs. Our commitment to purity and detailed product specifications ensures that your experimental outcomes are reproducible. We provide competitive Cinnamyl Acetoacetate price points, making it accessible for both academic research and industrial R&D projects. Whether you need small research quantities or larger pilot-scale batches, our supply capabilities are designed to meet your evolving requirements.

To advance your organic synthesis projects, consider incorporating Cinnamyl Acetoacetate (CAS 57582-46-4) into your reaction schemes. Contact us to learn more about its availability and to obtain a quotation. We are dedicated to providing the high-quality chemical building blocks that drive innovation in chemistry.