The intricate process of peptide synthesis demands precision at every step to ensure high yields and the desired stereochemical purity. For researchers and manufacturers, selecting the right reagents and additives can make a significant difference. Among the array of chemical compounds employed, 3-Hydroxy-1,2,3-benzotriazin-4(3H)-one, often referred to by its acronym HOOBT (CAS 28230-32-2), has emerged as a valuable tool.

As a prominent peptide coupling reagent, HOOBT plays a crucial role in mitigating a common challenge: racemization. When synthesizing peptides, especially with carbodiimides like Dicyclohexylcarbodiimide (DCC), the desired stereochemistry can be compromised. HOOBT acts as an effective additive, significantly decreasing the extent of this unwanted side reaction. This leads to a purer final product, which is critical for pharmaceutical applications and advanced research.

The benefits of incorporating HOOBT into your synthesis protocol are manifold. Firstly, it directly contributes to improved overall synthesis yields. By preventing the formation of undesired enantiomers, more of the target peptide is produced, making the process more efficient and cost-effective. This is particularly important for large-scale production where even small percentage improvements in yield can translate into substantial savings.

For those looking to purchase this essential chemical intermediate, sourcing from reliable manufacturers is key. As a leading supplier in China, we offer high-purity HOOBT, ensuring consistent quality and performance for your critical applications. Our commitment as a manufacturer means we understand the chemical properties and rigorous standards required for such reagents. Whether you need a small quantity for laboratory research or bulk supply for industrial production, exploring options from trusted suppliers can secure your supply chain.

The price of HOOBT can vary based on purity, quantity, and the supplier. When considering a purchase, it’s advisable to request quotes from multiple manufacturers to find the best value. Understanding the typical applications, such as its use in solid-phase and solution-phase peptide synthesis, helps in determining the exact grade and quantity needed. The continued demand for high-quality synthetic peptides ensures that reagents like HOOBT will remain vital components in the synthetic chemist's toolkit.

In conclusion, 3-Hydroxy-1,2,3-benzotriazin-4(3H)-one is more than just another chemical; it's a performance enhancer for peptide synthesis. Its ability to reduce racemization and boost yields makes it an indispensable additive for any researcher or manufacturer focused on delivering high-quality peptide products. We encourage you to inquire about our supply of this critical reagent and discover how our commitment as a manufacturer can benefit your procurement needs.