The pharmaceutical industry constantly seeks innovative molecular structures to develop novel therapeutics. Key to this process is the availability of high-quality, specialized chemical intermediates that enable the synthesis of complex drug molecules. 2,3,4-Trifluorobromobenzene, CAS number 176317-02-5, is one such critical intermediate, offering unique advantages in drug discovery and development. Its fluorinated structure and reactive bromine atom make it an invaluable tool for medicinal chemists and process development engineers.

The Significance of Fluorine in Pharmaceuticals

Introducing fluorine atoms into drug molecules can significantly impact their pharmacokinetic and pharmacodynamic profiles. Fluorine's high electronegativity and small atomic radius can enhance metabolic stability by blocking oxidation sites, increase lipophilicity for better cell membrane penetration, and alter the electronic properties of functional groups, leading to improved receptor binding. This often translates to increased drug efficacy and reduced side effects.

2,3,4-Trifluorobromobenzene as a Pharmaceutical Intermediate

2,3,4-Trifluorobromobenzene (CAS: 176317-02-5) serves as a crucial synthon for introducing the trifluorobromophenyl moiety into potential drug candidates. Its utility stems from:

  • Versatile Reactivity: The bromine atom can participate in a wide range of cross-coupling reactions (e.g., Suzuki, Sonogashira, Buchwald-Hartwig), allowing for the straightforward construction of C-C, C-N, and C-O bonds. This enables medicinal chemists to efficiently build complex molecular scaffolds.
  • Fluorine Introduction: It provides a pre-functionalized aromatic ring with strategically placed fluorine atoms, simplifying the synthesis of fluorinated pharmaceuticals.
  • Building Block for APIs: It is utilized in the synthesis pathways for various classes of therapeutic agents, contributing to the development of novel treatments.

Sourcing and Procurement Considerations

When your R&D or manufacturing requires 2,3,4-trifluorobromobenzene, it is essential to partner with a reliable manufacturer. As a dedicated 2,3,4-trifluorobromobenzene supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. offers:

  • High Purity: Our product consistently meets purity requirements of ≥98.0% (GC), which is critical for sensitive pharmaceutical synthesis to ensure predictable outcomes and minimize impurities.
  • Consistent Supply: We understand the importance of a stable supply chain for drug development timelines. Our robust production capabilities ensure reliable availability.
  • Competitive Pricing: We strive to offer an attractive CAS 176317-02-5 price, making high-quality intermediates accessible for your projects.
  • Quality Assurance: We provide comprehensive documentation, including Certificates of Analysis, to guarantee the quality and specifications of our products.

If you are looking to buy 2,3,4-trifluorobromobenzene or need a dependable supplier for your pharmaceutical research, NINGBO INNO PHARMCHEM CO.,LTD. is your trusted partner. We are dedicated to supporting the pharmaceutical industry by providing essential building blocks that accelerate the discovery and development of new medicines.