Organic Synthesis Intermediates: Focus on 1,4-Dibromobutane (CAS 110-52-1)
The backbone of modern chemical synthesis relies heavily on a range of well-defined intermediates, compounds that serve as critical stepping stones in the creation of more complex molecules. Among these, 1,4-Dibromobutane (CAS: 110-52-1) stands out due to its versatile reactivity and essential role in various synthetic pathways. Presented as a colorless to pale yellow transparent liquid, this organic compound is a cornerstone for many processes in the pharmaceutical, agrochemical, and fine chemical industries. For those looking to buy 1,4-Dibromobutane, understanding its specifications and sourcing it from a reliable manufacturer is paramount for achieving synthesis success.
1,4-Dibromobutane is characterized by its bifunctional nature, featuring two bromine atoms located at opposite ends of a four-carbon chain. This structural attribute makes it an excellent difunctional alkylating agent. The bromine atoms are good leaving groups, readily undergoing nucleophilic substitution reactions. This allows chemists to effectively introduce a four-carbon linker into other molecules or to facilitate intramolecular cyclization reactions. For example, it is a key precursor in the synthesis of cyclic ethers like tetrahydrofuran (THF) and various heterocyclic compounds vital for drug development. When you purchase 1,4-Dibromobutane, opting for a product with high purity, such as our ≥99.0% assay, ensures efficient and clean reactions, minimizing impurities that can plague sensitive syntheses.
Beyond its role in forming rings, 1,4-Dibromobutane is crucial for extending carbon chains and creating specific molecular architectures. It can react with two moles of a nucleophile, effectively bridging two different molecular fragments. This capability is highly valued in creating complex organic molecules, including certain types of polymers and specialized functional materials. Researchers and industrial chemists often seek out this specific intermediate when precise chain lengths and predictable reactivity are required. For these demanding applications, sourcing 1,4-Dibromobutane with low moisture content (≤500ppm) is essential to prevent unwanted side reactions, a specification we diligently maintain.
The physical properties of 1,4-Dibromobutane contribute to its ease of handling in laboratory and industrial settings. Its density is approximately 1.808, and it boils at 63-65°C. Being a liquid at most ambient temperatures (melting point -20°C) simplifies its transfer and use in reaction vessels. When procuring chemicals, especially from international suppliers, it is crucial to ensure that they have a robust quality assurance system. Manufacturers in China, such as ourselves, often provide competitive pricing and a stable supply chain, but rigorous vetting of quality control processes is always recommended. We package our 1,4-Dibromobutane in standard 250 kg drums, offering reliability for bulk purchases.
In conclusion, 1,4-Dibromobutane is an indispensable organic synthesis intermediate due to its unique bifunctional reactivity. Its applications in forming cyclic compounds and acting as a carbon chain extender are fundamental to many chemical manufacturing processes. For organizations aiming to buy high-quality 1,4-Dibromobutane, partnering with a trusted manufacturer and supplier like us guarantees the purity and reliability necessary for synthesis success. We are committed to providing this vital chemical building block with exceptional quality and service. Contact us today for a quote and to discuss how we can meet your chemical sourcing needs.
Perspectives & Insights
Bio Analyst 88
“It can react with two moles of a nucleophile, effectively bridging two different molecular fragments.”
Nano Seeker Pro
“This capability is highly valued in creating complex organic molecules, including certain types of polymers and specialized functional materials.”
Data Reader 7
“Researchers and industrial chemists often seek out this specific intermediate when precise chain lengths and predictable reactivity are required.”