Understanding Phenylsilane: Properties, Applications, and Quality Assurance
NINGBO INNO PHARMCHEM CO.,LTD. provides a detailed overview of phenylsilane (CAS 694-53-1), a key chemical intermediate valued for its specific properties and broad applications in organic synthesis. This colorless, clear liquid is characterized by its high purity (99% min) and its significant utility as an active amidation reagent, facilitating the synthesis of carboxamides and peptides.
The physical characteristics of phenylsilane are well-defined, including its boiling point of 119.3 ± 9.0 °C at 760 mmHg and a density of 0.877 g/mL at 25 °C. These properties, along with its melting point of -64 to -68 °C, are critical for its handling and reaction optimization. Its chemical formula, C6H8Si, and molecular weight of 108.213 further define its role in chemical reactions.
Phenylsilane's primary function as an active amidation reagent makes it indispensable for forming amide bonds, a common and important linkage in many organic molecules. Its applicability in both solution-phase and solid-phase chemistry allows for flexibility in synthetic design. For instance, in the realm of peptide synthesis, phenylsilane aids in the precise coupling of amino acids, ensuring the structural integrity required for biological activity. This makes it a valuable component for research in medicinal chemistry and drug discovery.
The quality assurance provided by NINGBO INNO PHARMCHEM CO.,LTD. for phenylsilane is paramount. Each batch undergoes rigorous quality testing, including NMR and HPLC analysis, to confirm its 99% minimum purity. This commitment to quality ensures that researchers can rely on phenylsilane for consistent and reproducible results in their demanding synthetic procedures. Our satisfaction guarantee further underscores our confidence in the product’s performance.
In summary, phenylsilane is a crucial chemical intermediate that offers significant advantages in amidation and peptide synthesis. Its well-defined properties, combined with NINGBO INNO PHARMCHEM's dedication to high purity and quality control, make it an essential reagent for advancing organic synthesis and chemical research.
Perspectives & Insights
Data Seeker X
“Phenylsilane's primary function as an active amidation reagent makes it indispensable for forming amide bonds, a common and important linkage in many organic molecules.”
Chem Reader AI
“Its applicability in both solution-phase and solid-phase chemistry allows for flexibility in synthetic design.”
Agile Vision 2025
“For instance, in the realm of peptide synthesis, phenylsilane aids in the precise coupling of amino acids, ensuring the structural integrity required for biological activity.”