For research and development scientists, the success of a project often hinges on the quality and availability of the chemical intermediates used. 3-chloro-1,1,1-trifluoropropan-2-one (CAS 431-37-8) is one such compound that plays a critical role in various advanced synthesis projects, particularly in the pharmaceutical and fine chemical sectors. Understanding its properties, applications, and how to efficiently procure it is essential for any R&D professional.

Key Properties and Characteristics

3-chloro-1,1,1-trifluoropropan-2-one, identified by CAS 431-37-8, is characterized by its chemical structure which includes a trifluoromethyl group and a chlorine atom adjacent to a carbonyl group. This arrangement makes it a highly reactive and versatile molecule. Typically, it is supplied as a clear liquid with a purity of at least 95%. Its boiling point is around 71-72°C at standard pressure, and its density is approximately 1.422 g/cm³. These physical attributes are important for handling, storage, and reaction design. For R&D scientists, the purity is a critical parameter, ensuring predictable reaction outcomes and minimizing side products.

Applications in Research and Development

The primary use of 3-chloro-1,1,1-trifluoropropan-2-one is as an intermediate in organic synthesis. Its ability to introduce the trifluoromethyl group is highly valued. This group can significantly enhance the biological activity and pharmacokinetic profiles of drug candidates. Therefore, it is extensively used in the synthesis of pharmaceutical intermediates and active pharmaceutical ingredients (APIs). Furthermore, its reactivity allows it to be used in the preparation of various agrochemicals and specialty chemicals. Researchers often rely on this compound for building complex molecular architectures where fluorination is key to achieving desired properties.

Efficient Sourcing for R&D Projects

When procuring chemicals for R&D, scientists often need smaller quantities for initial screening and then larger volumes as projects progress. Identifying reliable manufacturers who can supply consistently high-quality material is crucial. Sourcing from China-based suppliers, such as NINGBO INNO PHARMCHEM CO.,LTD., offers a practical solution for many research institutions. We understand the needs of R&D scientists and strive to provide excellent product quality, competitive pricing, and prompt delivery. Whether you need a few grams for lab-scale experiments or kilograms for pilot studies, we are equipped to meet your demands.

Partnering with a Chemical Supplier

For any scientist or procurement specialist looking to buy 3-chloro-1,1,1-trifluoropropan-2-one (CAS 431-37-8), engaging with experienced manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. is a strategic move. We ensure product traceability, provide necessary documentation, and maintain stringent quality control. This allows R&D teams to focus on their experimental work without concerns about the reliability of their starting materials. Contact us today to discuss your requirements and secure your supply of this vital chemical intermediate.