In the pursuit of efficient and effective chemical synthesis, a deep understanding of the properties of key intermediates is crucial. 2,6-Dibromoanisole (CAS 38603-09-7) is a compound whose physical and chemical characteristics dictate its utility across various industrial sectors, most notably in fine chemical and pharmaceutical manufacturing. As a liquid at room temperature with a melting point of 13°C, it presents distinct handling and reactivity profiles.

Physically, 2,6-Dibromoanisole is described as a clear liquid. Its boiling point is approximately 254°C, indicating a relatively low volatility under standard conditions, which aids in its handling during synthesis. The density of the compound is around 1.823 g/mL, a characteristic often relevant for volumetric calculations in chemical processes. Its refractive index, typically around 1.5920 to 1.5960, can be used as an additional parameter for quality control and identification. These physical attributes are important for procurement managers and lab technicians when assessing the material they intend to buy.

Chemically, the presence of two bromine atoms on the aromatic ring significantly influences its reactivity. These halogens make the molecule susceptible to various nucleophilic substitution reactions and palladium-catalyzed cross-coupling reactions, such as Suzuki, Stille, or Buchwald-Hartwig couplings. This reactivity is precisely why 2,6-Dibromoanisole is a valuable intermediate. It acts as a versatile synthon, allowing chemists to introduce complex functionalities onto the anisole core. For researchers, this means it can be a starting point for creating a wide range of novel organic compounds.

The primary applications stemming from these properties include its use as a building block in organic synthesis and as a critical intermediate in the production of pharmaceuticals, such as Lusutrombopag. The compound’s defined purity, often greater than 97%, ensures predictable reaction outcomes, which is essential for reproducible results in both research and industrial settings. When considering a purchase, understanding that these properties directly translate into its value proposition is key for any B2B buyer.

For those looking to acquire 2,6-Dibromoanisole, understanding its specifications—from physical state to chemical reactivity—is as important as finding a reliable supplier who can offer it at a competitive price. Whether for R&D purposes or larger-scale manufacturing, these properties are fundamental to its successful integration into chemical processes. By appreciating these details, procurement professionals can make informed decisions when sourcing this important organic intermediate.