In the realm of chemical synthesis, understanding the properties and applications of key intermediates is fundamental to successful research and development. 2-(Trifluoromethyl)phenyl Isothiocyanate, a compound identified by CAS number 1743-86-8, stands out as a versatile and important building block. This article provides a detailed look into its physical and chemical characteristics, explores its diverse applications, and emphasizes the importance of sourcing from a dependable manufacturer and supplier. For chemists looking to buy this compound, a thorough understanding is essential for optimal utilization.

2-(Trifluoromethyl)phenyl Isothiocyanate is characterized by its appearance as a pale yellow transparent liquid. Its physical and chemical properties are well-defined, contributing to its utility in various synthetic processes. Key parameters include a density of approximately 1.3 ± 0.1 g/cm³ and a boiling point of 239.8 ± 40.0 °C at 760 mmHg. These values are critical for chemists when designing reaction conditions and purification procedures. The molecular formula C8H4F3NS and a molecular weight of 203.184 provide the precise elemental composition. Furthermore, its flash point of 98.8 ± 27.3 °C is an important safety consideration for handling and storage. The specification of ≥99.0% purity is a testament to its quality, ensuring minimal interference from impurities in complex synthetic pathways.

The primary application of 2-(Trifluoromethyl)phenyl Isothiocyanate lies in its role as an organic synthesis intermediate. Its structure, featuring both a trifluoromethyl group and an isothiocyanate moiety, makes it invaluable for introducing specific functionalities and properties into target molecules. The trifluoromethyl group is highly prized in pharmaceuticals and agrochemicals for its ability to enhance lipophilicity, metabolic stability, and bioavailability. The isothiocyanate group (-NCS) is a potent electrophile that readily undergoes addition reactions with various nucleophiles, such as amines, alcohols, and thiols. This reactivity allows for the efficient synthesis of thioureas, heterocycles, and other complex organic structures. For example, its reaction with amines forms substituted thioureas, a common structural motif in many biologically active compounds. Researchers looking to synthesize novel compounds can leverage this intermediate to create molecules with enhanced properties.

When sourcing specialty chemicals, the choice of supplier is critical. NINGBO INNO PHARMCHEM CO.,LTD. is a leading manufacturer and supplier in China, dedicated to providing high-quality chemical intermediates. We ensure that our 2-(Trifluoromethyl)phenyl Isothiocyanate is produced under strict quality control measures to achieve the specified ≥99.0% assay. This commitment guarantees consistency and reliability for our clients. We understand the importance of competitive price in the chemical industry, and we strive to offer cost-effective solutions without compromising on quality. Our packaging options typically include 200 kg/drum, but we are also flexible in accommodating specific customer requirements for purchase.

The versatility of 2-(Trifluoromethyl)phenyl Isothiocyanate extends to various fields beyond general organic synthesis. It is a key component in the development of pharmaceuticals, agrochemicals, and advanced materials. Its ability to introduce beneficial trifluoromethyl groups makes it attractive for designing drugs with improved pharmacokinetic profiles and pesticides with enhanced potency and selectivity. The compound is also explored in material science for creating functional polymers and specialty chemicals. For those seeking to buy this compound, partnering with a reliable manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. ensures that you receive a product that meets your exact specifications, supported by excellent customer service and technical expertise. We are your trusted source for high-quality chemical intermediates.

In conclusion, 2-(Trifluoromethyl)phenyl Isothiocyanate is a vital chemical intermediate with a well-defined set of properties and broad applications in organic synthesis. Its role in pharmaceuticals, agrochemicals, and material science underscores its significance. For researchers and industrial chemists looking to buy this compound, choosing a reputable manufacturer and supplier in China like NINGBO INNO PHARMCHEM CO.,LTD. is essential for ensuring product quality, competitive price, and reliable supply. Contact us today for a quote and discover the benefits of partnering with a leading chemical provider.