In the expansive world of chemical compounds, understanding the nuances of specific molecules is key to unlocking their potential for innovation. Chlorodimethylisobutylsilane (CAS 27490-70-6), also known by synonyms such as Isobutyldimethylchlorosilane, is a significant organosilicon compound with a defined set of properties and applications that make it valuable in various scientific and industrial contexts.

Physically, Chlorodimethylisobutylsilane is described as a clear liquid. This physical characteristic is important for handling and storage, suggesting it remains in a liquid state under typical laboratory and industrial conditions. Its molecular formula, C6H15ClSi, reveals a relatively small molecule comprising carbon, hydrogen, chlorine, and silicon. The molecular weight is approximately 150.72 g/mol. Key physical parameters like boiling point, often cited between 131-133°C, and flash point, around 18°C, provide critical data for safe handling, transportation, and processing. Its density is typically around 0.863 g/cm³. Importantly, due to the reactive silicon-chlorine bond, it is sensitive to moisture and reacts with water, a property that dictates careful storage and handling procedures, often requiring inert atmospheres.

Chemically, Chlorodimethylisobutylsilane belongs to the class of alkylsilyl halides. The presence of the Si-Cl bond makes it a highly reactive species, readily undergoing nucleophilic substitution reactions. This reactivity is precisely what drives its primary applications. In the field of proteomics, it functions as an effective derivatizing agent. By reacting with polar functional groups on peptides and proteins, it can enhance their volatility and chromatographic behavior, thereby improving detection sensitivity in mass spectrometry. This makes it an invaluable tool for researchers investigating complex biological systems.

Beyond proteomics, Chlorodimethylisobutylsilane serves as a versatile intermediate in organic synthesis. It is a key building block for the creation of more complex organosilicon compounds, including specialty silicones, resins, and surface modifiers. Its ability to introduce the isobutyldimethylsilyl group into molecules allows for tailored material properties. For professionals looking to buy this compound, it is essential to partner with reliable manufacturers and suppliers, such as those found in China. When considering a purchase, information regarding purity (typically ≥95%), packaging options, and shipping logistics is crucial. Understanding the price point from various suppliers will also inform the procurement decision.

In essence, Chlorodimethylisobutylsilane is a chemically reactive and industrially significant organosilicon intermediate. Its well-defined properties and versatile applications, particularly in proteomics and advanced synthesis, underscore its importance. Sourcing this compound from reputable chemical suppliers ensures access to the quality and consistency required for critical research and manufacturing endeavors.