For chemists and researchers, a thorough understanding of a chemical's properties and safe handling procedures is fundamental to successful and secure laboratory operations. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing comprehensive support for the chemicals we supply, including 1-(2-Bromo-4-fluorophenyl)ethanone (CAS 1006-39-9). This compound, a valuable intermediate in various synthesis processes, requires careful consideration of its characteristics.

1-(2-Bromo-4-fluorophenyl)ethanone, also known by synonyms such as 2'-Bromo-4'-fluoroacetophenone, is a pale yellow oil. Its key physical properties include a melting point typically in the range of 48-50°C and a boiling point of approximately 150°C at 12 mmHg. The density is reported around 1.535 ± 0.06 g/cm³. These properties are essential for understanding its behavior during storage, handling, and reaction processes. For example, its relatively low melting point means it can be handled as a solid or a viscous liquid depending on ambient temperature.

From a chemical perspective, 1-(2-Bromo-4-fluorophenyl)ethanone (C8H6BrFO) is characterized by the reactivity of its halogen substituents and its ketone functional group. The bromine atom is susceptible to nucleophilic substitution and can participate in various metal-catalyzed cross-coupling reactions. The fluorine atom, while generally less reactive, influences the electronic properties of the molecule and can affect the reactivity of neighboring positions. The carbonyl group of the ketone can undergo nucleophilic addition, reduction, or condensation reactions, making it a versatile component in multi-step syntheses. As a key organic synthesis building block, its diverse reactivity is a significant advantage.

Safe handling of 1-(2-Bromo-4-fluorophenyl)ethanone is crucial. Standard laboratory safety practices should always be observed. This includes working in a well-ventilated area, preferably under a fume hood, to avoid inhalation of any vapors. Appropriate personal protective equipment (PPE) should be worn, including chemical-resistant gloves, safety goggles, and protective clothing, to prevent skin and eye contact. While specific toxicity data might vary, compounds of this nature are generally treated with caution due to potential irritant properties. The hazard statements often associated with such chemicals include skin and eye irritation.

When looking to buy 1-(2-Bromo-4-fluorophenyl)ethanone 97% or higher purity, it is important to source from reputable suppliers like NINGBO INNO PHARMCHEM CO.,LTD. We ensure that our products are accompanied by appropriate safety data sheets (SDS) that detail hazards, first-aid measures, firefighting procedures, and accidental release measures. Proper storage conditions, typically in a cool, dry place in tightly sealed containers, are also vital to maintain product integrity and safety.

In summary, understanding the physical and chemical properties of 1-(2-Bromo-4-fluorophenyl)ethanone is key to its effective use in synthesis. By adhering to strict safety protocols and sourcing from trusted 2'-Bromo-4'-fluoroacetophenone suppliers like NINGBO INNO PHARMCHEM CO.,LTD., researchers can confidently and safely utilize this valuable intermediate in their laboratory work, driving forward advancements in chemistry and related fields.