For anyone working with or looking to procure Bis(diisopropylamino)chlorophosphine (CAS: 56183-63-2), a thorough understanding of its physical and chemical properties, as well as its safety considerations, is vital. As a key intermediate in various synthetic processes, knowing these details ensures efficient and safe handling, from laboratory research to industrial-scale manufacturing.

Physical and Chemical Properties of Bis(diisopropylamino)chlorophosphine

Bis(diisopropylamino)chlorophosphine typically presents as a white to off-white powder or crystalline solid. Its chemical formula is C12H28ClN2P, with a molecular weight of 266.79 g/mol. A critical characteristic is its sensitivity to both air and moisture. This means it can degrade or react when exposed to atmospheric conditions, necessitating storage under an inert atmosphere (such as nitrogen or argon) and in tightly sealed containers. Suppliers commonly package this compound to maintain its integrity.

Other notable properties include:

  • Melting Point: Often cited in the range of 100-104°C or 100.0°C to 110.0°C, indicating its solid state at room temperature.
  • Reactivity: As a chlorophosphine, it is a reactive species, readily participating in nucleophilic substitution reactions. This reactivity is key to its utility in synthesis but also highlights the need for careful handling.
  • Solubility: While it reacts with water, it is typically soluble in common organic solvents.

Safety Considerations and Handling Precautions

Given its reactivity and sensitivity, Bis(diisopropylamino)chlorophosphine is classified as a hazardous substance. Safety Data Sheets (SDS) provided by manufacturers and suppliers are the primary source for detailed handling information. Key safety points include:

  • Corrosive Nature: It can cause severe skin burns and eye damage (indicated by GHS hazard statements like H314). Appropriate personal protective equipment (PPE) such as gloves, eye protection (goggles or face shield), and protective clothing is mandatory.
  • Reaction with Water: It reacts violently with water, producing hazardous fumes. Contact with moisture must be strictly avoided during handling and storage.
  • Inhalation Hazard: Avoid breathing dust or vapors. Work in a well-ventilated area or use local exhaust ventilation (fume hood).
  • Storage: Store in a cool, dry, well-ventilated place, away from incompatible materials (especially water and oxidizing agents), and preferably under an inert atmosphere.

Where to Buy and Get Information

When looking to buy Bis(diisopropylamino)chlorophosphine, always obtain the latest SDS from your chosen supplier. Reputable manufacturers and distributors will readily provide this document, along with product specifications and Certificates of Analysis. Understanding these properties is not only crucial for safe laboratory practices but also for ensuring that the material meets the precise requirements for your intended chemical synthesis, whether for pharmaceutical, agrochemical, or materials science applications.