Understanding the Properties and Synthesis of 2-Fluoro-6-methoxyaniline
For chemists and researchers involved in fine chemical manufacturing, a deep understanding of the properties and synthesis of key intermediates is essential. 2-Fluoro-6-methoxyaniline (CAS 446-61-7) is one such compound, offering a unique combination of functionalities that make it valuable in various chemical processes.
Physically, 2-Fluoro-6-methoxyaniline is often described as a clear, peach or khaki-colored liquid with a density around 1.176 g/cm³. It has a boiling point of approximately 208 °C, indicating its stability under typical reaction conditions. The compound's molecular formula is C7H8FNO, with a molecular weight of 141.14 g/mol. These properties are critical for handling, storage, and reaction planning in organic intermediate synthesis.
The synthesis of 2-Fluoro-6-methoxyaniline typically involves the reduction of a nitro precursor. A common route involves using a palladium on carbon (Pd/C) catalyst under a hydrogen atmosphere to reduce 3-fluoro-2-nitroanisole. This process, often carried out in ethanol, yields the desired aniline derivative with good efficiency, as reported in various chemical literature and patents. The availability of these synthetic pathways from reliable suppliers in China makes it accessible for widespread use.
When considering the purchase of this chemical, purity is a key concern. High purity levels (e.g., >=97%) are vital for applications in pharmaceutical building blocks and specialized organic synthesis. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. are committed to delivering products that meet these stringent requirements, ensuring that your projects benefit from consistent quality. We aim to be your preferred supplier for high purity fluorinated anilines and other essential chemical intermediates, supporting your research and production needs efficiently.
Physically, 2-Fluoro-6-methoxyaniline is often described as a clear, peach or khaki-colored liquid with a density around 1.176 g/cm³. It has a boiling point of approximately 208 °C, indicating its stability under typical reaction conditions. The compound's molecular formula is C7H8FNO, with a molecular weight of 141.14 g/mol. These properties are critical for handling, storage, and reaction planning in organic intermediate synthesis.
The synthesis of 2-Fluoro-6-methoxyaniline typically involves the reduction of a nitro precursor. A common route involves using a palladium on carbon (Pd/C) catalyst under a hydrogen atmosphere to reduce 3-fluoro-2-nitroanisole. This process, often carried out in ethanol, yields the desired aniline derivative with good efficiency, as reported in various chemical literature and patents. The availability of these synthetic pathways from reliable suppliers in China makes it accessible for widespread use.
When considering the purchase of this chemical, purity is a key concern. High purity levels (e.g., >=97%) are vital for applications in pharmaceutical building blocks and specialized organic synthesis. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. are committed to delivering products that meet these stringent requirements, ensuring that your projects benefit from consistent quality. We aim to be your preferred supplier for high purity fluorinated anilines and other essential chemical intermediates, supporting your research and production needs efficiently.
Perspectives & Insights
Data Seeker X
“It has a boiling point of approximately 208 °C, indicating its stability under typical reaction conditions.”
Chem Reader AI
“These properties are critical for handling, storage, and reaction planning in organic intermediate synthesis.”
Agile Vision 2025
“The synthesis of 2-Fluoro-6-methoxyaniline typically involves the reduction of a nitro precursor.”