In the pharmaceutical industry, ingredient selection is governed by strict regulations, demanding high purity, consistent quality, and proven efficacy. Propylene Glycol (PG), identified by its CAS number 57-55-6, is a vital chemical compound that plays a crucial role as both a solvent and an excipient in a wide range of pharmaceutical formulations. Its unique properties make it an indispensable component for ensuring the stability, delivery, and overall effectiveness of medications.

Propylene Glycol: A Pharmaceutical Workhorse

Pharmaceutical-grade Propylene Glycol is characterized by its exceptional purity, low toxicity, and excellent solvent capabilities. As a solvent, PG can dissolve poorly water-soluble active pharmaceutical ingredients (APIs), enabling their effective administration through various routes, including oral, topical, and parenteral (injectable) forms. This capability is critical for developing stable and bioavailable drug products.

Its humectant properties also contribute to the stability of pharmaceutical formulations, preventing degradation and maintaining product integrity over time. Furthermore, PG's ability to reduce the freezing point of aqueous solutions makes it valuable in injectable formulations that may be exposed to freezing temperatures during storage or transport.

Key Pharmaceutical Applications of Propylene Glycol

Propylene Glycol is utilized across a broad spectrum of pharmaceutical applications:

  • Oral Medications: PG serves as a solvent and viscosity-increasing agent in liquid oral dosage forms, such as syrups and suspensions, improving palatability and ease of administration.
  • Topical Preparations: In creams, ointments, and gels, it functions as a solvent, humectant, and penetration enhancer, aiding in the delivery of active ingredients to the skin.
  • Injectable Formulations: PG is used as a co-solvent in some intramuscular and intravenous injections, helping to solubilize poorly water-soluble drugs and improve drug delivery.
  • Ophthalmic Solutions: Its properties help stabilize ophthalmic preparations and improve drug penetration into the eye.

Reliable Sourcing for Pharmaceutical Needs

For pharmaceutical manufacturers and formulators, securing a reliable supply of high-purity, pharmaceutical-grade Propylene Glycol is non-negotiable. It is essential to partner with a manufacturer and supplier that adheres to Good Manufacturing Practices (GMP) and can provide comprehensive documentation, including Certificates of Analysis (CoA) and Safety Data Sheets (SDS). When exploring the propylene glycol price in China or other regions, prioritize suppliers who can guarantee consistent quality and regulatory compliance.

We understand the critical demands of the pharmaceutical industry. As a trusted supplier of Propylene Glycol, we are committed to providing pharmaceutical-grade material that meets your stringent requirements. We encourage you to contact us for a quote and to discuss how our reliable supply chain and commitment to quality can support your pharmaceutical development and manufacturing needs.