In the intricate field of biochemistry and protein science, precise control over molecular interactions is often the key to unlocking new discoveries and applications. Citraconic Anhydride, a chemical compound readily available from trusted suppliers like NINGBO INNO PHARMCHEM CO.,LTD., offers a unique advantage: reversible modification of proteins. This capability makes it an invaluable tool for researchers and manufacturers in the life sciences sector.

Citraconic Anhydride, known by its CAS number 616-02-4, is chemically characterized as a 3-methylfuran-2,5-dione. Its primary utility in protein modification stems from its ability to react with primary amine groups, particularly the lysine residues in proteins. This reaction forms an amide linkage and introduces a carboxylate group, effectively blocking the amine. The crucial aspect here is the reversibility: under acidic conditions (typically pH 4), this modification can be hydrolyzed, releasing the original amine and citraconic acid. This feature allows for a temporary blocking strategy, enabling site-specific labeling or conjugation that can later be undone.

The ability to reversibly block amine groups is critical for various biochemical processes. For instance, in protein purification or cross-linking experiments, temporarily masking certain reactive sites can guide subsequent reactions to desired locations. This level of control is essential for creating well-defined protein conjugates, developing diagnostic assays, or modifying enzymes for improved stability and function. Researchers looking to buy Citraconic Anhydride for these sophisticated biochemical applications will find it a powerful reagent.

As a leading manufacturer and supplier of high-quality chemicals, NINGBO INNO PHARMCHEM CO.,LTD. provides Citraconic Anhydride that meets the demanding purity requirements of biochemical research. Our consistent supply chain ensures that laboratories and production facilities can rely on us for their ongoing needs. Whether you are investigating protein structure, developing new therapeutic proteins, or engineering biomaterials, the accessibility of dependable Citraconic Anhydride is vital.

The application of Citraconic Anhydride in protein chemistry is a testament to its versatility. Its selective reaction with amines, combined with its pH-dependent reversibility, offers a nuanced approach to protein manipulation. Understanding these properties is key for any scientist or procurement manager looking to leverage this reagent. We encourage you to inquire about our Citraconic Anhydride, as we are committed to supporting your scientific endeavors with quality products and competitive pricing.

In summary, Citraconic Anhydride (CAS 616-02-4) represents a significant advancement in biochemical reagents, particularly for its role in reversible protein modification. For those seeking a reliable source of this essential compound, NINGBO INNO PHARMCHEM CO.,LTD. offers the quality and service necessary for cutting-edge research and development. Contact us to secure your supply and explore the potential of this remarkable chemical.