The pharmaceutical industry continuously seeks novel molecular scaffolds to develop more effective and safer therapeutic agents. Within this landscape, specific organic intermediates play a crucial role, acting as foundational building blocks for complex drug molecules. One such compound of growing importance is 1,3-Diazaspiro[4.5]decane-2,4-dione, identified by CAS number 702-62-5. Its unique spirocyclic structure offers intriguing possibilities for medicinal chemists.

Understanding the Structure and Properties

1,3-Diazaspiro[4.5]decane-2,4-dione is a derivative of hydantoin, featuring a spirocyclic arrangement where a cyclohexane ring is fused to a hydantoin ring at a single carbon atom. This structural motif imbues it with distinct chemical properties. With a molecular formula of C8H12N2O2 and a molecular weight of approximately 168.20 g/mol, it is typically supplied as a white crystalline solid with a high melting point (217-219°C). This stability makes it amenable to various synthetic manipulations. As a key component for pharmaceutical intermediates wholesale, its consistent quality and purity are paramount.

Applications in Drug Discovery and Development

The spirohydantoin core of 1,3-Diazaspiro[4.5]decane-2,4-dione provides a rigid three-dimensional framework that can be functionalized to interact with biological targets. This makes it an attractive starting material for:

  • Novel Drug Scaffolds: Medicinal chemists can derivatize the molecule to explore a wide range of biological activities, potentially leading to new drug candidates for various diseases. Its structure offers a unique approach compared to more conventional ring systems.
  • Fragment-Based Drug Design: The compound itself or its derivatives can serve as valuable fragments in fragment-based drug discovery, where small molecular fragments are screened for binding affinity to target proteins.
  • Synthesis of Bioactive Compounds: Research has shown its utility in the synthesis of compounds exhibiting potential antiviral, anti-inflammatory, or other therapeutic properties.

When considering the buy 1,3-diazaspiro[4.5]decane-2,4-dione for these applications, sourcing from a reputable organic chemistry intermediates manufacturer is crucial. A reliable supplier ensures that the material meets the stringent purity requirements necessary for pharmaceutical research and development, thereby avoiding potential setbacks in drug discovery pipelines.

Procurement for Pharmaceutical Needs

For pharmaceutical companies and contract research organizations (CROs), securing a consistent and high-quality supply of 1,3-Diazaspiro[4.5]decane-2,4-dione (CAS 702-62-5) is vital. Partnering with a leading 1,3-diazaspiro[4.5]decane-2,4-dione supplier in China can offer significant advantages, including competitive pricing and assured availability. We understand the importance of traceability and quality assurance in the pharmaceutical supply chain, and we are dedicated to providing material that meets global standards.

The ongoing demand for innovative therapeutics ensures that compounds like 1,3-Diazaspiro[4.5]decane-2,4-dione will remain important in the years to come. By collaborating with experienced manufacturers, the pharmaceutical industry can continue to advance the frontiers of medicine.