In the dynamic world of chemical synthesis, specific molecular building blocks are essential for driving innovation. 1,3-Dichlorotetramethyldisiloxane (CAS 2401-73-2) stands out as a highly versatile organosilicon compound, playing a crucial role in both the development of advanced silicone materials and as a pivotal intermediate in pharmaceutical manufacturing. For R&D scientists and procurement specialists, understanding its chemical properties and application potential is key to leveraging its benefits.

Chemical Profile and Properties

1,3-Dichlorotetramethyldisiloxane is a clear liquid with a molecular formula of C4H12Cl2OSi2. Its structure, featuring two silicon atoms linked by an oxygen atom and each bonded to two methyl groups and one chlorine atom, grants it significant reactivity. This reactivity, particularly the presence of labile chlorine atoms, makes it an excellent precursor for creating new silicon-oxygen bonds and modifying surfaces. Key physical properties, such as its boiling point of 138°C and a flash point of 15°C, are critical for safe handling and process design. As a moisture-sensitive compound, proper storage and handling protocols are essential for maintaining its integrity.

Applications in Silicone Chemistry

The silicone industry relies heavily on compounds like 1,3-Dichlorotetramethyldisiloxane for the synthesis of a vast array of products. Its ability to undergo hydrolysis and condensation reactions allows for the controlled formation of siloxane chains. This is fundamental for:

  • Polymerization: It acts as a monomer or co-monomer in the production of silicone polymers, including polydimethylsiloxanes (PDMS). By controlling the reaction conditions and co-reactants, manufacturers can tailor the molecular weight, viscosity, and physical properties of the resulting silicone materials.
  • Surface Modification: The reactive chlorine groups can be used to graft siloxane chains onto various substrates, imparting properties such as hydrophobicity, lubrication, or biocompatibility. This is vital in developing advanced coatings and materials for medical devices, electronics, and textiles.
  • Precursor for Other Silanes: It serves as a starting material for synthesizing other functionalized silanes and siloxanes with specific applications in adhesives, sealants, and elastomers (CASE applications).

Significance in Pharmaceutical Manufacturing

The pharmaceutical sector leverages 1,3-Dichlorotetramethyldisiloxane primarily as a versatile pharmaceutical intermediate. Its well-defined structure and reactivity allow for precise chemical transformations, enabling the synthesis of complex organic molecules that form the basis of many pharmaceuticals. For R&D scientists, sourcing high-purity 1,3-Dichlorotetramethyldisiloxane is crucial to ensure the efficacy and safety of the final drug products. Pharmaceutical manufacturers often seek suppliers who can guarantee consistent quality and provide detailed documentation, such as Certificates of Analysis.

Where to Buy and What to Consider

When sourcing 1,3-Dichlorotetramethyldisiloxane, it is essential to partner with reputable manufacturers and suppliers. We, as a dedicated manufacturer, offer this critical intermediate with guaranteed purity and consistent supply. When you buy from us, you benefit from our expertise in chemical production and our commitment to quality. We provide detailed specifications, safety data sheets (SDS), and are ready to discuss bulk pricing and delivery options to meet your specific project timelines and budget. Consider us your trusted partner for all your organosilicon intermediate needs.