In the realm of synthetic organic chemistry, the ability to precisely construct complex molecules is often dependent on the availability and quality of specific chemical intermediates. 1-Chloro-8-iodooctane, identified by its CAS number 74962-58-6, is one such compound that plays a significant role in enabling a diverse array of chemical transformations. Its unique structural features, combined with high purity, make it a valuable asset for researchers and manufacturers alike. Understanding its properties and applications is crucial for anyone involved in advanced chemical synthesis.

Chemical Profile of 1-Chloro-8-iodooctane

1-Chloro-8-iodooctane is a linear haloalkane with the molecular formula C8H16ClI. Its key characteristic is the presence of two different halogen atoms – chlorine and iodine – at the terminal positions of an eight-carbon chain. This difunctionalization is the basis of its synthetic utility. The carbon-iodine bond is weaker and more polarizable than the carbon-chlorine bond, leading to a difference in reactivity. This allows chemists to perform selective reactions, such as nucleophilic substitutions or coupling reactions, by targeting either the iodine or the chlorine atom under specific conditions. With a reported boiling point of 96-97°C, it is typically supplied as a pale yellow transparent liquid in 200 kg drums, though custom packaging is often available. Due to its inherent instability, proper storage, including refrigeration and protection from light, is essential to maintain its quality.

Versatile Intermediate for Synthesis

The application scope of 1-chloro-8-iodooctane is extensive, primarily within organic synthesis:

  • Chain Extension and Functionalization: The distinct reactivity of the two halogen atoms allows for sequential reactions, enabling the precise extension of carbon chains or the introduction of different functional groups at specific positions. This is invaluable for building complex molecular frameworks.
  • Synthesis of Pharmaceutical Compounds: In the pharmaceutical industry, intermediates like 1-chloro-8-iodooctane are critical for constructing novel drug candidates and optimizing synthesis routes for existing APIs. Its structure can be a starting point for various complex organic molecules.
  • Development of Specialty Chemicals: Beyond pharmaceuticals, this compound finds use in the creation of specialty chemicals, including monomers for advanced polymers, surfactants, and agrochemical intermediates. Manufacturers seeking reliable chemical raw materials often look to secure a consistent supply.
  • Cross-Coupling Reactions: The halogen atoms make it suitable for various cross-coupling reactions, such as Grignard or organolithium reactions, and transition-metal-catalyzed couplings, further expanding its synthetic versatility.

Sourcing and Partnership for Success

For procurement managers and research scientists, sourcing 1-chloro-8-iodooctane from a reputable manufacturer is key. Our commitment as a leading supplier in China ensures that you receive a product with guaranteed purity (≥99.0%), meeting the rigorous standards required for sophisticated chemical synthesis. We understand the importance of a stable supply chain, offering the product in standard packaging and adhering to best practices for handling and storage. We encourage potential clients to request a quote and discuss their needs, as we are dedicated to supporting your scientific endeavors with high-quality intermediates and reliable service. Partnering with us means gaining access to a crucial component for your synthesis projects, backed by a commitment to quality and efficiency.