The pharmaceutical industry constantly seeks novel and efficient synthetic routes to develop life-saving medications. At the heart of many of these processes lie versatile chemical intermediates, and 1-Fluoro-4-iodobutane (CAS: 372-91-8) stands out as a crucial component. This organohalide, with its distinctive fluorine and iodine functionalities, offers unique reactivity that is highly prized by medicinal chemists and process engineers.

Understanding the Chemical Profile of 1-Fluoro-4-iodobutane

Chemically known as 1-fluoro-4-iodobutane, this compound’s molecular formula is C4H8FI, with a molecular weight of approximately 202.01 g/mol. Its utility stems from its ability to act as a bifunctional alkylating agent. The iodine atom is a good leaving group, readily participating in nucleophilic substitution reactions, while the fluorine atom can impart specific electronic or physical properties to the final molecule. This dual nature allows for targeted modifications and the construction of complex molecular architectures that are essential for drug discovery and development. When sourcing this material, looking for suppliers who can provide detailed specifications like density (around 1.6765) and boiling point (e.g., 52.5-53.5 °C at 13 Torr) ensures you are receiving a product suitable for precise synthetic applications.

Applications in Drug Discovery and Development

1-Fluoro-4-iodobutane plays a pivotal role in several stages of pharmaceutical synthesis. It is frequently employed in the preparation of active pharmaceutical ingredients (APIs) and their intermediates. Its ability to introduce a fluorinated butyl chain into a molecule is particularly valuable, as fluorine substitution can significantly impact a drug's metabolic stability, lipophilicity, and binding affinity to its biological target. Researchers often search for 'buy 1-fluoro-4-iodobutane' when designing synthetic strategies for new chemical entities. For example, it can be used to alkylate amines, alcohols, or carbon nucleophiles, creating diverse pharmacophores. We, as a dedicated manufacturer and supplier, understand these critical needs and ensure our 1-Fluoro-4-iodobutane is available at high purity, supporting your innovation from lab-scale research to commercial production.

Partnering with Reliable Suppliers for Pharmaceutical Intermediates

The integrity of pharmaceutical synthesis relies heavily on the quality of starting materials and intermediates. Therefore, selecting a trusted '1-fluoro-4-iodobutane supplier' is paramount. A reputable supplier not only guarantees product purity but also provides comprehensive documentation, including COAs and adherence to industry standards. Whether you are looking for bulk supply or require custom manufacturing services, partnering with an experienced manufacturer ensures continuity and quality. If you are seeking to purchase 1-Fluoro-4-iodobutane, exploring options from established Chinese manufacturers can offer both cost-effectiveness and reliable access to this indispensable chemical building block.

In conclusion, 1-Fluoro-4-iodobutane is an indispensable intermediate for the pharmaceutical industry, enabling the synthesis of complex and potent drug candidates. Engaging with knowledgeable suppliers ensures access to high-quality material, facilitating breakthroughs in drug discovery.