In the realm of medical diagnostics, the development of effective contrast agents is critical for enhancing imaging clarity and providing accurate patient information. Central to many of these advancements is the macrocyclic compound 1,4,7,10-Tetraazacyclododecane. For professionals involved in pharmaceutical development and procurement, understanding this key intermediate is essential. This article highlights its significance and the considerations for sourcing.

1,4,7,10-Tetraazacyclododecane, often referred to by its acronym or as a cyclen derivative, is a cyclam-type macrocycle possessing a unique structure that makes it an excellent chelating agent. Its ability to form highly stable complexes with paramagnetic metal ions, such as gadolinium (Gd3+), is the foundation for its widespread use in Magnetic Resonance Imaging (MRI) contrast agents. When purchasing this compound, its purity level, typically around 98.0%-102.0%, directly impacts the performance and safety of the final diagnostic product.

The specific physical properties of 1,4,7,10-Tetraazacyclododecane, such as its appearance as a white to light yellow crystalline powder and its defined melting point (108-114°C), are key indicators of quality. These parameters are meticulously controlled by reputable manufacturers to ensure batch-to-batch consistency. For R&D scientists and product formulators, sourcing from a reliable manufacturer that provides detailed specifications and analytical data is crucial for successful product development.

The demand for advanced MRI contrast agents means that the supply chain for essential intermediates like 1,4,7,10-Tetraazacyclododecane must be robust. Many global pharmaceutical companies rely on specialized chemical suppliers, particularly those based in China, for their raw material needs. When you choose to buy 1,4,7,10-Tetraazacyclododecane from a leading manufacturer, you benefit from competitive pricing and a stable supply, which are critical for large-scale production and clinical availability.

Beyond its role in MRI, the chelating properties of 1,4,7,10-Tetraazacyclododecane also lend themselves to other applications in coordination chemistry and the development of targeted radiopharmaceuticals for PET and SPECT imaging. Its versatility as a ligand makes it a valuable compound for companies looking to innovate in diagnostic and therapeutic fields.

In essence, understanding the chemical attributes and sourcing strategies for 1,4,7,10-Tetraazacyclododecane is vital for the advancement of medical imaging technologies. Partnering with trusted chemical suppliers who prioritize quality and reliability ensures that critical intermediates are available for developing life-saving diagnostic tools. Consider us your go-to manufacturer for this essential chemical.