The pharmaceutical industry relies heavily on a diverse range of chemical intermediates to synthesize active pharmaceutical ingredients (APIs) and complex drug molecules. 2-Bromophenetole, identified by its CAS number 583-19-7, is a noteworthy intermediate that plays a significant role in this sector. For R&D chemists and procurement managers, understanding its properties, applications, and reliable sourcing channels is essential. This article highlights the importance of 2-Bromophenetole in pharmaceutical synthesis and guides you on how to procure it.

2-Bromophenetole: A Pharmaceutical Building Block

2-Bromophenetole, chemically known as 1-bromo-2-ethoxybenzene, is an aromatic compound with the molecular formula C8H9BrO. It is characterized as a colourless oil, with a boiling point of approximately 223°C and a density of around 1.3646. Its molecular structure, featuring an ethoxy group and a bromine atom on a benzene ring, makes it a versatile synthon. The bromine atom, in particular, is a reactive site that facilitates various coupling and substitution reactions crucial for building complex molecular architectures.

Applications in Drug Discovery and Development

The pharmaceutical applications of 2-Bromophenetole are extensive:

  • Synthesis of APIs: It serves as a critical starting material or intermediate in the multi-step synthesis of numerous APIs. Its aryl bromide functionality can be readily transformed using established synthetic methodologies like palladium-catalyzed cross-coupling reactions (e.g., Suzuki-Miyaura coupling), which are widely employed in pharmaceutical manufacturing.
  • Lead Optimization: In drug discovery, chemists often modify existing lead compounds to improve efficacy, safety, or pharmacokinetic profiles. 2-Bromophenetole can be used to introduce specific aromatic ether functionalities into candidate molecules.
  • Research and Development: Academic and industrial researchers utilize it for exploring novel synthetic routes and discovering new therapeutic agents. Many scientists actively search to buy 2-Bromophenetole for their innovative projects.

When engaging in pharmaceutical synthesis, the purity and consistency of intermediates are paramount. Therefore, R&D teams prioritize sourcing from manufacturers who can guarantee high purity levels (often >97% GC) and provide comprehensive Certificates of Analysis (CoAs).

Sourcing 2-Bromophenetole for Pharmaceutical Use

Finding a reliable 2-Bromophenetole supplier China can offer distinct advantages for pharmaceutical companies, including competitive pricing and robust supply chain capabilities. When considering procurement:

  • Supplier Qualification: It is essential to partner with manufacturers who understand and adhere to the stringent quality requirements of the pharmaceutical industry.
  • Technical Support: Access to technical data and responsive customer support can significantly aid in the successful integration of the intermediate into your synthesis protocols.
  • Price Inquiry: Obtaining quotes for CAS 583-19-7 price from multiple sources helps in making informed purchasing decisions and managing project budgets.

For procurement specialists, initiating contact with manufacturers is the most effective way to secure the necessary quantities of 2-Bromophenetole. Whether you need small research quantities or large-scale production batches, engaging directly with suppliers allows for the most accurate pricing and delivery information for 1-bromo-2-ethoxybenzene.

In conclusion, 2-Bromophenetole is a vital chemical intermediate with significant applications in pharmaceutical synthesis. By understanding its chemical properties and adhering to best practices in sourcing, pharmaceutical companies can ensure the efficient and cost-effective acquisition of this critical compound, thereby supporting the development of new and improved medicines.